Overview

  • Product name
  • Description
    Rabbit polyclonal to TRAPPC2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 91-140 (QEDGIKNFFT DVYDLYIKFS MNPFYEPNSP IRSSAFDRKV QFLGKKHLLS) of Human TRAPPC2 (NP_055378).

  • Positive control
    • Human fetal spleen lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab89952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 16 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
  • Tissue specificity
    Widely expressed.
  • Involvement in disease
    Defects in TRAPPC2 are the cause of spondyloepiphyseal dysplasia tarda (SEDT) [MIM:313400]. SEDT is an X-linked recessive disorder of endochondral bone formation.
  • Sequence similarities
    Belongs to the TRAPP small subunits family. Sedlin subfamily.
  • Cellular localization
    Cytoplasm > perinuclear region. Endoplasmic reticulum. Golgi apparatus. Localized in perinuclear granular structures.
  • Information by UniProt
  • Database links
  • Alternative names
    • hYP38334 antibody
    • MBP 1 interacting protein 2A antibody
    • MBP-1-interacting protein 2A antibody
    • MIP 2A antibody
    • MIP-2A antibody
    • MIP2A antibody
    • SEDL antibody
    • Sedlin antibody
    • SEDLP antibody
    • SEDT antibody
    • Spondyloepiphyseal dysplasia tarda protein antibody
    • Spondyloepiphyseal dysplasia, late antibody
    • TPPC2_HUMAN antibody
    • Trafficking protein particle complex 2 antibody
    • Trafficking protein particle complex subunit 2 antibody
    • TRAPPC2P1 antibody
    • TRS20 antibody
    • ZNF547L antibody
    see all

Anti-TRAPPC2 antibody images

  • Anti-TRAPPC2 antibody (ab89952) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 16 kDa
    Observed band size : 16 kDa

References for Anti-TRAPPC2 antibody (ab89952)

ab89952 has not yet been referenced specifically in any publications.

Product Wall



In your email you noted ab89920 in the subject line and ab89952 in the body of the email. Just in case I have recommended HRP secondary antibodies for both:

The anti-TRAPPC2 antibody ab89952 is a rabbit polyclonal product. A good HR...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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