Overview

  • Product name
    Anti-TREML1 antibody [EP15294]
    See all TREML1 primary antibodies
  • Description
    Rabbit monoclonal [EP15294] to TREML1
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human TREML1 aa 50-200. The exact sequence is proprietary.
    Database link: Q86YW5

  • Positive control
    • Human spleen tissue; Jurkat cells.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab192619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
ICC/IF 1/50.

Target

  • Function
    Cell surface receptor that may play a role in the innate and adaptive immune response.
  • Tissue specificity
    Detected in platelets, monocytic leukemia and in T-cell leukemia.
  • Sequence similarities
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Cellular localization
    Cell membrane. Cytoplasm. Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis.
  • Information by UniProt
  • Database links
  • Alternative names
    • dJ238O23.3 antibody
    • GLTL1825 antibody
    • MGC119173 antibody
    • PRO3438 antibody
    • TLT 1 antibody
    • TLT-1 antibody
    • TLT1 antibody
    • TREM like transcript 1 antibody
    • Trem like transcript 1 protein antibody
    • Trem-like transcript 1 protein antibody
    • TREML 1 antibody
    • Treml1 antibody
    • Triggering receptor expressed on myeloid cells like 1 antibody
    • Triggering receptor expressed on myeloid cells like protein 1 antibody
    • Triggering receptor expressed on myeloid cells-like protein 1 antibody
    • TRML1_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling TREML1 with ab192619 at 1/1000 dilution (0.08μg/ml). A Ready to use HRP Polymer for Rabbit IgG (prediluted) was used as secondary. Counterstain: Hematoxylin.

  • Immunofluorescent analysis of Jurkat cells (4% Paraformaldehyde-fixed, 0.1% tritonX-100 permeabilized) labeling TREML1 with ab192619 at 1/50 dilution (1.6 μg/ml). A Goat anti rabbit IgG (Alexa Fluor488) at 1/400 dilution (ab150077) was used as secondary antibody.  Counterstain: DAPI.

References

ab192619 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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