Overview

  • Product name
  • Description
    Rabbit polyclonal to TREX1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 182-369 of Human TREX1 (UniProt ID: Q9NSU2).

  • Positive control
    • HepG2 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab151434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.

Target

  • Relevance
    TREX1 is the major 3'->5' DNA exonuclease in human cells. The protein is a non processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A mediated cell death. Mutations in this gene result in Aicardi Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • 3' 5' exonuclease TREX1 antibody
    • 3' repair exonuclease 1 antibody
    • AGS1 antibody
    • AGS5 antibody
    • CRV antibody
    • Deoxyribonuclease III, dnaQ/mutD (E. coli) like antibody
    • DKFZp434J0310 antibody
    • DNase III antibody
    • DRN3 antibody
    • HERNS antibody
    • Three prime repair exonuclease 1 antibody
    • TREX1 antibody
    see all

Images

  • Anti-TREX1 antibody (ab151434) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 39 kDa

References

ab151434 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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