Anti-TRH-R antibody (ab72179)
Key features and details
- Rabbit polyclonal to TRH-R
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TRH-R antibody
See all TRH-R primary antibodies -
Description
Rabbit polyclonal to TRH-R -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Opossum -
Immunogen
Synthetic peptide corresponding to Human TRH-R aa 350-400 (C terminal).
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Positive control
- Human brain lysate. Human thyroid tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.2% Gelatin, PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72179 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
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IHC-P |
Use a concentration of 10 µg/ml.
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Notes |
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WB
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). |
IHC-P
Use a concentration of 10 µg/ml. |
Target
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Function
Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 281549 Cow
- Entrez Gene: 7201 Human
- Entrez Gene: 22045 Mouse
- Entrez Gene: 25570 Rat
- Omim: 188545 Human
- SwissProt: O46639 Cow
- SwissProt: P34981 Human
- SwissProt: P21761 Mouse
see all -
Alternative names
- Thyroliberin receptor antibody
- Thyrotropin Releasing Hormone Receptor antibody
- Thyrotropin-releasing hormone receptor antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (4)
ab72179 has been referenced in 4 publications.
- Pech-Pool S et al. Thyrotropin-Releasing Hormone (TRH) and Somatostatin (SST), but not Growth Hormone-Releasing Hormone (GHRH) nor Ghrelin (GHRL), Regulate Expression and Release of Immune Growth Hormone (GH) from Chicken Bursal B-Lymphocyte Cultures. Int J Mol Sci 21:N/A (2020). PubMed: 32093298
- Pijnacker T et al. TRH-induced secretion of adrenocorticotropin and cortisol in dogs with pituitary-dependent hypercortisolism. Vet Q 38:72-78 (2018). PubMed: 30362899
- Zhang Y et al. The potential role of thyrotropin-releasing hormone in colonic dysmotility induced by water avoidance stress in rats. Neuropeptides N/A:N/A (2018). WB, IHC-P . PubMed: 29803395
- Puissant MM et al. RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO2 insensitive brown Norway rat. J Physiol 593:415-30 (2015). PubMed: 25630262