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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: 2% Sucrose, PBS
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Function Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity.
Tissue specificity Highly expressed in peripheral blood leukocytes.
Sequence similarities Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily. Contains 1 protein kinase domain.
Cellular localization Cytoplasm. Cytoplasm > cytoskeleton. May associate with the cytoskeleton.
Information by UniProt
Anti-TRIB2 antibody images
Western blot - TRIB2 antibody (ab84683)
References for Anti-TRIB2 antibody (ab84683)
This product has been referenced in:
et al. TRIB2 inhibits Wnt/ß-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ß-TrCP, COP1 and Smurf1, in liver cancer cells. FEBS Lett 588:4334-41 (2014).
Read more (PubMed: 25311538) »
et al. Ubiquitin E3 ligase SCF(ß-TRCP) regulates TRIB2 stability in liver cancer cells. Biochem Biophys Res Commun 441:555-9 (2013).
Read more (PubMed: 24211582) »
See all 3 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"