Anti-TRIM antibody [TRIM-04] (Phycoerythrin) (ab36414)

Overview

  • Product name
    Anti-TRIM antibody [TRIM-04] (Phycoerythrin)
    See all TRIM primary antibodies
  • Description
    Mouse monoclonal [TRIM-04] to TRIM (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Specificity
    We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to intracellular amino acids 29/186 of Human TRIM

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 15mM Sodium Azide
    Constituents: 0.2% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purification notes
    Purified by size-exclusion chromatography.
  • Clonality
    Monoclonal
  • Clone number
    TRIM-04
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab36414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/50. ab91363-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
  • Tissue specificity
    Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).
  • Developmental stage
    Strongly expressed in fetal thymus at weeks 17-24 of gestation. Undetectable in bone marrow and fetal liver.
  • Post-translational
    modifications
    Phosphorylated on tyrosines by LCK or FYN upon TCR activation.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HSPC062 antibody
    • pp29/30 antibody
    • T cell receptor interacting molecule antibody
    • T-cell receptor-associated transmembrane adapter 1 antibody
    • T-cell receptor-interacting molecule antibody
    • TCRIM antibody
    • TRAT1 antibody
    • TRAT1_HUMAN antibody
    • TRIM antibody
    see all

Images

  • Flow cytometry analysis of Human peripheral blood cells labeling TRIM with ab36414. 

References

ab36414 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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