Overview

  • Product name
  • Description
    Goat polyclonal to TRIM35
  • Specificity
    This antibody is expected to recognise both human isoforms.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide: ERSPDVSPGPSRS, corresponding to N terminal amino acids 2-14 of Human TRIM35.

  • General notes
    Principal Names – Likely ortholog of mouse macrophage-derived apoptosis-inducing RBCC (RING-B-box-coiled-coil) protein. Official Gene Symbol - TRIM35. GenBank Accession Number – NP_055881; NP_741983.

Properties

Applications

Our Abpromise guarantee covers the use of ab4388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 57 kDa).Can be blocked with Human TRIM35 peptide (ab23034).

Target

  • Function
    May play a role as a tumor suppressor. Implicated in the cell death mechanism.
  • Sequence similarities
    Belongs to the TRIM/RBCC family.
    Contains 1 B box-type zinc finger.
    Contains 1 B30.2/SPRY domain.
    Contains 1 RING-type zinc finger.
  • Domain
    The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.
  • Cellular localization
    Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.
  • Information by UniProt
  • Database links
  • Alternative names
    • 0710005M05Rik antibody
    • A430106H13Rik antibody
    • AW046487 antibody
    • Hemopoietic lineage switch protein 5 antibody
    • HLS5 antibody
    • KIAA1098 antibody
    • Macrophage derived apoptosis inducing RBCC protein antibody
    • MAIR antibody
    • MGC17233 antibody
    • mKIAA1098 antibody
    • NC8 antibody
    • Protein MAIR antibody
    • Protein Nc8 antibody
    • TRI35_HUMAN antibody
    • TRIM35 antibody
    • Tripartite motif containing 35 antibody
    • Tripartite motif containing protein 35 antibody
    • Tripartite motif-containing protein 35 antibody
    see all

Images

References

ab4388 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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