Overview

  • Product name
    Anti-TRIM66 antibody
  • Description
    Rabbit polyclonal to TRIM66
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 359-408 (GSLQCSALLP REKELACSPH PPKLLQPWLE TQPPVEQEST SQRLGQQLTS) of Human TRIM66 (NP_055633)

  • Positive control
    • A549 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab108445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 135 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association.
  • Sequence similarities
    Contains 2 B box-type zinc fingers.
    Contains 1 bromo domain.
    Contains 1 PHD-type zinc finger.
  • Cellular localization
    Nucleus. Forms discrete foci within the centromeric chromocenter and surrounding nucleoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • TRI66_HUMAN antibody
    • Trim66 antibody
    • Tripartite motif-containing protein 66 antibody

Images

  • Anti-TRIM66 antibody (ab108445) at 1 µg/ml + A549 cells at 10 µg

    Predicted band size : 135 kDa

References

ab108445 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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