Anti-Triosephosphate isomerase antibody (HRP) (ab124174)

Overview

  • Product nameAnti-Triosephosphate isomerase antibody (HRP)
    See all Triosephosphate isomerase primary antibodies
  • Description
    Goat polyclonal to Triosephosphate isomerase (HRP)
  • ConjugationHRP
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Dog
  • Immunogen

    Synthetic peptide:

    C-LKPEFVDIINAKQ

    , corresponding to C terminal amino acids 274-286 of Human Triosephosphate isomerase according to NP_000356.1; NP_001152759.1.

  • Positive control
    • Human liver lysates.
  • General notes

    Conjugated via amine groups to horseradish peroxidise.

Properties

Applications

Our Abpromise guarantee covers the use of ab124174 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 26 kDa.

Target

  • RelevanceTriosephosphate isomerase (TIM) catalyses the reversible interconversion of G3P and DHAP. Only G3P can be used in glycolysis, therefore TIM is essential for energy production, allowing two molecules of G3P to be produced for every glucose molecule, thereby doubling the energy yield. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
  • Cellular localizationCytoplasmic and Nuclear; extracellular vesicle exosome; extracellular space.
  • Database links
  • Alternative names
    • epididymis secretory protein Li 49 antibody
    • HEL-S-49 antibody
    • MGC88108 antibody
    • TIM antibody
    • TPI 1 antibody
    • TPI antibody
    • TPI1 antibody
    • TPID antibody
    • Triose phosphate isomerase 1 antibody
    • Triose phosphate isomerase antibody
    • Triosephosphate isomerase 1 antibody
    • Triosephosphate isomerase antibody
    see all

Anti-Triosephosphate isomerase antibody (HRP) images

  • Anti-Triosephosphate isomerase antibody (HRP) (ab124174) at 1/1000 dilution + Human liver lysates in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 26 kDa


    Exposure time : 1 minute

References for Anti-Triosephosphate isomerase antibody (HRP) (ab124174)

ab124174 has not yet been referenced specifically in any publications.

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