Anti-Tripeptidyl peptidase II antibody (ab195645)

Overview

  • Product name
    Anti-Tripeptidyl peptidase II antibody
    See all Tripeptidyl peptidase II primary antibodies
  • Description
    Rabbit polyclonal to Tripeptidyl peptidase II
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) corresponding to Human Tripeptidyl peptidase II. Purified from erythrocytes.
    Database link: P29144

  • Positive control
    • Purified Tripeptidyl peptidase II

Properties

Applications

Our Abpromise guarantee covers the use of ab195645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 138 kDa.

Target

  • Relevance
    Tripeptidyl peptidase II is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It may be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Tripeptidyl peptidase II is a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.
  • Cellular localization
    Cytoplasmic
  • Database links
  • Alternative names
    • TPP II antibody
    • TPP2 antibody
    • Tripeptidyl aminopeptidase antibody
    • Tripeptidyl peptidase 2 antibody
    • Tripeptidyl peptidase II antibody
    see all

Images

  • Anti-Tripeptidyl peptidase II antibody (ab195645) at 1/1000 dilution + purified Tripeptidyl peptidase II at 1 µg

    Predicted band size : 138 kDa

References

ab195645 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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