Overview

  • Product nameAnti-TRK fused gene antibody
    See all TRK fused gene primary antibodies
  • Description
    Rabbit polyclonal to TRK fused gene
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Human, Chimpanzee, Monkey
    Predicted to work with: Mouse, Cow, Dog, Opossum
  • Immunogen

    Synthetic peptide (Human) corresponding to a region between residues 350-400 of TFG. (NP_006061).

  • Positive control
    • Human brain lysate Human small intestine tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab72126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 43 kDa).
IHC-P Use a concentration of 10 µg/ml.

Target

  • Tissue specificityUbiquitous.
  • Involvement in diseaseDefects in TFG are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TFG is found in thyroid papillary carcinomas. Translocation t(1;3)(q21;q11) with NTRK1. The TFG sequence is fused to the 3'-end of NTRK1 generating the TRKT3 (TRK-T3) fusion transcript.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ36137 antibody
    • HMSNP antibody
    • OTTHUMP00000214045 antibody
    • OTTHUMP00000214046 antibody
    • OTTHUMP00000214047 antibody
    • OTTHUMP00000214048 antibody
    • Protein TFG antibody
    • SPG57 antibody
    • TF6 antibody
    • TFG antibody
    • TFG_HUMAN antibody
    • TRK fused antibody
    • TRK fused gene antibody
    • TRK fused gene protein antibody
    • TRK-fused gene protein antibody
    • TRKT3 antibody
    • TRKT3 oncogene antibody
    see all

Anti-TRK fused gene antibody images

  • All lanes : Anti-TRK fused gene antibody (ab72126) at 0.5 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Human brain lysate with immunising peptide


    Predicted band size : 43 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)
  • ab72126, at 10µg/ml, staining TRK fused gene in human small intestine tissue.

References for Anti-TRK fused gene antibody (ab72126)

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"