Recombinant
RabMAb

Anti-TRK fused gene antibody [EPR8765(2)(B)] (ab150428)

Overview

  • Product name
    Anti-TRK fused gene antibody [EPR8765(2)(B)]
    See all TRK fused gene primary antibodies
  • Description
    Rabbit monoclonal [EPR8765(2)(B)] to TRK fused gene
  • Tested applications
    Suitable for: WB, IHC-P, Flow Cyt, ICC/IFmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • Positive control
    • Human fetal brain, 293T and HeLa cell lysates; Human colon tissue; HeLa cells.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab150428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 43 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/250 - 1/500.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Tissue specificity
      Ubiquitous.
    • Involvement in disease
      Defects in TFG are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TFG is found in thyroid papillary carcinomas. Translocation t(1;3)(q21;q11) with NTRK1. The TFG sequence is fused to the 3'-end of NTRK1 generating the TRKT3 (TRK-T3) fusion transcript.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ36137 antibody
      • HMSNP antibody
      • OTTHUMP00000214045 antibody
      • OTTHUMP00000214046 antibody
      • OTTHUMP00000214047 antibody
      • OTTHUMP00000214048 antibody
      • Protein TFG antibody
      • SPG57 antibody
      • TF6 antibody
      • TFG antibody
      • TFG_HUMAN antibody
      • TRK fused antibody
      • TRK fused gene antibody
      • TRK fused gene protein antibody
      • TRK-fused gene protein antibody
      • TRKT3 antibody
      • TRKT3 oncogene antibody
      see all

    Images

    • All lanes : Anti-TRK fused gene antibody [EPR8765(2)(B)] (ab150428) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : 293T cell lysate
      Lane 3 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 43 kDa
    • Immunohistochemical analysis of paraffin-embedded Human colon tissue labelling TRK fused gene with ab150428 at 1/50 dilution.
    • Immunofluorescent analysis of HeLa cells labelling TRK fused gene with ab150428 at 1/250 dilution.
    • Immunohistochemical analysis of paraffin embedded Human Lung adenocarcinoma tissue using ab150428 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded normal Human kidney tissue using ab150428 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded Human Ovarian carcinoma tissue using ab150428 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded Human Thyroid gland carcinoma tissue using ab150428 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using ab150428 showing +ve staining.

    References

    ab150428 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab150428.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up