Overview

  • Product name
    Anti-Tropomodulin 1 antibody
    See all Tropomodulin 1 primary antibodies
  • Description
    Rabbit polyclonal to Tropomodulin 1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 169-198 of Human Tropomodulin 1 (Accessions: NP_001159588.1, NP_003266.1, P28289)

  • Positive control
    • A549 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab124187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

Target

  • Function
    Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
  • Tissue specificity
    Highly expressed in the erythrocyte, heart and skeletal muscle.
  • Sequence similarities
    Belongs to the tropomodulin family.
  • Cellular localization
    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • D9S57E antibody
    • E Tmod antibody
    • E tropomodulin antibody
    • E-Tmod antibody
    • Erythrocyte tropomodulin antibody
    • ETMOD antibody
    • MGC124125 antibody
    • MGC124126 antibody
    • OTTHUMP00000021743 antibody
    • TMOD antibody
    • Tmod1 antibody
    • TMOD1 protein antibody
    • TMOD1_HUMAN antibody
    • Tropomodulin 1 antibody
    • Tropomodulin-1 antibody
    see all

Images

  • Anti-Tropomodulin 1 antibody (ab124187) at 1/100 dilution + A549 cell line lysates at 35 µg

    Predicted band size : 41 kDa

References

ab124187 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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