Anti-Troponin I fast + slow skeletal muscle antibody [7G2] (HRP) (ab24464)

Overview

  • Product nameAnti-Troponin I fast + slow skeletal muscle antibody [7G2] (HRP)
    See all Troponin I fast + slow skeletal muscle primary antibodies
  • Description
    Mouse monoclonal [7G2] to Troponin I fast + slow skeletal muscle (HRP)
  • ConjugationHRP
  • SpecificityDetects both fast and slow Troponin I from human skeletal muscle. Cross-reaction of this antibody with cardiac troponin I is less then 1.5%.
  • Tested applicationsSuitable for: WB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab24464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [12F10] to TNNI1 (ab8293). Use as Detection antibody.
AP Use at an assay dependent dilution.

Target

  • RelevanceTroponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue.
  • Cellular localizationCytoplasmic and Nuclear
  • Database links
  • Alternative names
    • AMCD2B antibody
    • DA2B antibody
    • DKFZp451O223 antibody
    • Fast twitch skeletal muscle troponin I antibody
    • FSSV antibody
    • fsTnI antibody
    • OTTHUMP00000014141 antibody
    • OTTHUMP00000014142 antibody
    • OTTHUMP00000014143 antibody
    • OTTHUMP00000033877 antibody
    • OTTHUMP00000033909 antibody
    • OTTHUMP00000033910 antibody
    • SSTNI antibody
    • TNN1 antibody
    • Troponin I fast twitch 2 antibody
    • Troponin I type 1 (skeletal, slow) antibody
    • Troponin I type 2 (skeletal, fast) antibody
    • Troponin I, fast skeletal muscle antibody
    • Troponin I, fast twitch isoform antibody
    • Troponin I, fast twitch skeletal muscle isoform antibody
    • Troponin I, skeletal, fast antibody
    • Troponin I, slow skeletal muscle antibody
    • Troponin I, slow twitch isoform antibody
    see all

References for Anti-Troponin I fast + slow skeletal muscle antibody [7G2] (HRP) (ab24464)

ab24464 has not yet been referenced specifically in any publications.

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