For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Rat monoclonal [MAC 145] to Troponin T1
Antibody reacts with troponin-T in Lethocerus, Drosophila and dragonfly muscles (flight and non-flight).
Drosophila melanogaster, Dragon fly, Waterbug
Does not react with:
Troponin-tropomyosin complex purified from Lethocerus indicus (Waterbug)flight muscle
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Electron Microscopy: Use at an assay dependent dilution.
ICC/IF: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 47 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Involvement in disease
Nemaline myopathy 5
Belongs to the troponin T family.
Information by UniProt
- ANM antibody
- MGC104241 antibody
- NEM5 antibody
References for Anti-Troponin T1 antibody [MAC 145] (ab50576)
This product has been referenced in:
- Gong H et al. Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1. Mol Med Rep 16:787-793 (2017).
Read more (PubMed: 28560388) »
- Agianian B et al. A troponin switch that regulates muscle contraction by stretch instead of calcium. EMBO J 23:772-9 (2004).
Read more (PubMed: 14765112) »
See all 5 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"