Overview

  • Product name
  • Description
    Goat polyclonal to TRP 7
  • Specificity
    This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1).
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Chicken
    Predicted to work with: Mouse, Rat, Guinea pig, Dog, Human, Pig
  • Immunogen

    Synthetic peptide, corresponding to internal sequence amino acids 731-743 (

    KLCKSKAKSCEND

    ) of Human TRP 7 (NP_065122.1).

  • Positive control
    • Chicken embryo heart NIH3T3 and KELLY cell lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab95466 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 100 kDa.

Target

  • Function
    Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
  • Sequence similarities
    Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily.
    Contains 4 ANK repeats.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Capacitative calcium channel TRPC7 antibody
    • cation channel, subfamily C, member 7 antibody
    • hTRP7 antibody
    • KNP3 antibody
    • Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7 antibody
    • mTRP7 antibody
    • Putative capacitative calcium channel antibody
    • Short transient receptor potential channel 7 antibody
    • Transient receptor potential cation channel subfamily C member 7 antibody
    • transient receptor potential-related channel 7, a novel putative Ca2+ channel protein antibody
    • Transient receptor protein 7 antibody
    • TRP 7 antibody
    • TRP-7 antibody
    • TRP7 protein antibody
    • TRPC 7 antibody
    • TrpC7 antibody
    • Trpc7 transient receptor potential cation channel, subfamily C, member 7 antibody
    • TRPC7_HUMAN antibody
    • TRPM2 antibody
    • Trrp8 antibody
    see all

References

ab95466 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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