Overview

  • Product name
    Anti-TRP 7 antibody [N64A/36]
    See all TRP 7 primary antibodies
  • Description
    Mouse monoclonal [N64A/36] to TRP 7
  • Tested applications
    Suitable for: WB, IHC-P, IHC-Fr, ICC/IF, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    LRVNKGKDI

    , corresponding to amino acids 854-862 of Human TRP 7 (UniProt Q9HCX4).

  • Positive control
    • Rat brain lysate
  • General notes

    The clone number has been updated from S64A-36 to N64A/36, both clone numbers name the same antibody clone.

     

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    N64A/36
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab93618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
IHC-Fr
ICC/IF
ICC
  • Application notes
    ICC: Use at a concentration of 0.1 - 1 µg/ml.
    ICC/IF: Use at a concentration of 1 - 10 µg/ml.
    IHC-P: Use at a concentration of 0.1 - 1 µg/ml.
    IHC-Fr: Use at a concentration of 0.1 - 1 µg/ml.
    WB: Use at a concentration of 1 - 10 µg/ml. Predicted molecular weight: 100 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
    • Sequence similarities
      Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily.
      Contains 4 ANK repeats.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Capacitative calcium channel TRPC7 antibody
      • cation channel, subfamily C, member 7 antibody
      • hTRP7 antibody
      • KNP3 antibody
      • Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7 antibody
      • mTRP7 antibody
      • Putative capacitative calcium channel antibody
      • Short transient receptor potential channel 7 antibody
      • Transient receptor potential cation channel subfamily C member 7 antibody
      • transient receptor potential-related channel 7, a novel putative Ca2+ channel protein antibody
      • Transient receptor protein 7 antibody
      • TRP 7 antibody
      • TRP-7 antibody
      • TRP7 protein antibody
      • TRPC 7 antibody
      • TrpC7 antibody
      • Trpc7 transient receptor potential cation channel, subfamily C, member 7 antibody
      • TRPC7_HUMAN antibody
      • TRPM2 antibody
      • Trrp8 antibody
      see all

    Images

    • Immunohistochemical detection of Trp7 using ab93618 in Mouse backskin tissue sections.


    • Predicted band size : 100 kDa
      Western blot detection of Trp7 in Rat brain membrane lysates using ab93618 at 1:1000 dilution.

    References

    This product has been referenced in:
    • Nakipova OV  et al. Store-operated Ca2+ entry supports contractile function in hearts of hibernators. PLoS One 12:e0177469 (2017). Read more (PubMed: 28531217) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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