Overview

  • Product nameAnti-TRPC1 antibody
    See all TRPC1 primary antibodies
  • Description
    Goat polyclonal to TRPC1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide to an internal region of Human TRPC1 conjugated to KLH.

  • Positive control
    • Human cortex, Human Prostate (fibromuscular stroma)

Properties

Applications

Our Abpromise guarantee covers the use of ab110837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionThought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
  • Tissue specificitySeems to be ubiquitous.
  • Sequence similaritiesBelongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
    Contains 4 ANK repeats.
  • Post-translational
    modifications
    Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HTRP 1 antibody
    • HTRP1 antibody
    • MGC133334 antibody
    • MGC133335 antibody
    • Mtrp1 antibody
    • Short transient receptor potential channel 1 antibody
    • Transient receptor potential canonical 1 antibody
    • Transient receptor potential cation channel subfamily C member 1 antibody
    • Transient receptor potential channel 1 antibody
    • Transient receptor protein 1 antibody
    • TRP 1 antibody
    • TRP 1 protein antibody
    • Trp related protein 1 antibody
    • TRP-1 antibody
    • TRP1 antibody
    • TRP1 protein antibody
    • TrpC1 antibody
    • Trpc1 transient receptor potential cation channel subfamily C member 1 antibody
    • TRPC1_HUMAN antibody
    • Trrp1 antibody
    see all

Anti-TRPC1 antibody images

  • ab110837 at 3.75 µg/ml staining TRPC1 in Human cortex by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • ab110837 at 3.75 µg/ml staining TRPC1 in Human Prostate (fibromuscular stroma) by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

References for Anti-TRPC1 antibody (ab110837)

ab110837 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110837.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"