Overview

  • Product name
    Anti-TRPC4AP antibody
  • Description
    Rabbit polyclonal to TRPC4AP
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 81-294 of Human TRPC4AP (UniProt: Q8TEL6).

  • Positive control
    • A549, HeLa, HepG2 and HCT116 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab153810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 91 kDa.

Target

  • Function
    Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
  • Pathway
    Protein modification; protein ubiquitination.
  • Information by UniProt
  • Database links
  • Alternative names
    • C20orf188 antibody
    • TRPC4AP antibody
    • Chromosome 20 open reading frame 188 antibody
    • Protein TAP1 antibody
    • Protein TRUSS antibody
    • Short transient receptor potential channel 4 associated protein antibody
    • Short transient receptor potential channel 4-associated protein antibody
    • TAP1 protein antibody
    • TNF receptor ubiquitous scaffolding/signaling protein antibody
    • TNF-receptor ubiquitous scaffolding/signaling protein antibody
    • TP4AP_HUMAN antibody
    • Transient receptor potential cation channel, subfamily C, member 4 associated protein antibody
    • Trp4 associated protein antibody
    • Trp4-associated protein antibody
    • Trpc4 associated protein antibody
    • Trpc4-associated protein antibody
    • TRPC4AP antibody
    • TRRP4AP antibody
    • TRUSS antibody
    • Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein antibody
    see all

Images

  • Anti-TRPC4AP antibody (ab153810) at 1/1000 dilution + A549 whole cell
    lysate at 30 µg

    Predicted band size: 91 kDa



    7.5% SDS PAGE

References

ab153810 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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