Overview

  • Product nameAnti-TRPC4AP antibody
    See all TRPC4AP primary antibodies
  • Description
    Goat polyclonal to TRPC4AP
  • SpecificityThis antibody is expected to recognize both reported TRPC4AP isoforms (NP_955400.1; NP_056453.1).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide: C-

    KLTQETTYPNTYIFD

    , corresponding to internal sequence amino acids 118-132 of Human TRPC4AP (NP_056453.1; NP_955400.1).

  • Positive control
    • U937 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90431 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 91 kDa).

Target

  • FunctionSubstrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
  • PathwayProtein modification; protein ubiquitination.
  • Information by UniProt
  • Database links
  • Alternative names
    • C20orf188 antibody
    • TRPC4AP antibody
    • Chromosome 20 open reading frame 188 antibody
    • Protein TAP1 antibody
    • Protein TRUSS antibody
    • Short transient receptor potential channel 4 associated protein antibody
    • Short transient receptor potential channel 4-associated protein antibody
    • TAP1 protein antibody
    • TNF receptor ubiquitous scaffolding/signaling protein antibody
    • TNF-receptor ubiquitous scaffolding/signaling protein antibody
    • TP4AP_HUMAN antibody
    • Transient receptor potential cation channel, subfamily C, member 4 associated protein antibody
    • Trp4 associated protein antibody
    • Trp4-associated protein antibody
    • Trpc4 associated protein antibody
    • Trpc4-associated protein antibody
    • TRPC4AP antibody
    • TRRP4AP antibody
    • TRUSS antibody
    • Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein antibody
    see all

Anti-TRPC4AP antibody images

References for Anti-TRPC4AP antibody (ab90431)

ab90431 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90431.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"