Overview

  • Product name
    Anti-TRPC5 antibody
  • Description
    Rabbit polyclonal to TRPC5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to to a region within N terminal amino acids 253-283 of Human TRPC5 (NP_036603.1).

  • Positive control
    • HL60 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 111 kDa.

Target

  • Function
    Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.
  • Tissue specificity
    Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.
  • Sequence similarities
    Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC5 sub-subfamily.
    Contains 4 ANK repeats.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Htrp 5 antibody
    • Htrp-5 antibody
    • Htrp5 antibody
    • Short transient receptor potential channel 5 antibody
    • Transient receptor potential cation channel subfamily C member 5 antibody
    • Transient receptor potential channel 5 antibody
    • Transient receptor protein 5 antibody
    • TRP 5 antibody
    • TRP-5 antibody
    • TRP5 antibody
    • TRPC 5 antibody
    • TrpC5 antibody
    • TRPC5_HUMAN antibody
    see all

Images

  • Anti-TRPC5 antibody (ab116326) at 1/100 dilution + HL60 cell line lysate at 35 µg

    Predicted band size : 111 kDa

References

ab116326 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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