Overview

  • Product nameAnti-TRPM6 antibody
  • Description
    Guinea pig polyclonal to TRPM6
  • Tested applicationsSuitable for: IHC-Frmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    GCERDKNRSSLERHTRL

Properties

Applications

Our Abpromise guarantee covers the use of ab47017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/100 - 1/1000.

Target

  • RelevanceTRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
  • Cellular localizationMulti-pass membrane protein.
  • Database links
  • Alternative names
    • CHAK2 antibody
    • Channel kinase 2 antibody
    • HMGX antibody
    • HOMG antibody
    • HSH antibody
    • Melastatin related TRP cation channel 6 antibody
    • Transient receptor potential cation channel subfamily M member 6 antibody
    see all

Anti-TRPM6 antibody images

  • Immunohistochemical staining of frozen rat kidney tissue, using ab47017. Secondary staining was carried out using a Cy3 conjugated antibody.

References for Anti-TRPM6 antibody (ab47017)

This product has been referenced in:
  • Boyden LM  et al. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482:98-102 (2012). Read more (PubMed: 22266938) »

See 1 Publication for this product

Product Wall

Thank you for your reply and your patience with this response.

I heard back from the lab in Australia, and unfortunately none of our anti-TRPM6 antibodies (ab47017, ab62990, ab63089, ab72153, ab74850, ab77499, ab79227) show significant homolo...

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Thank you for your inquiry.

I just wanted to give you an update.

We have 7 anti-TRPM6 antibodies in the catalogue. We wouldn't expect ab47017 to work in bovine, because the immunogen sequence really does not show any homology with b...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"