Anti-Tryptophan Hydroxylase (phospho S58) antibody (ab61068)

Overview

  • Product nameAnti-Tryptophan Hydroxylase (phospho S58) antibody
    See all Tryptophan Hydroxylase primary antibodies
  • Description
    Rabbit polyclonal to Tryptophan Hydroxylase (phospho S58)
  • Specificityab61068 detects endogenous levels of Tryptophan Hydroxylase only when phosphorylated at serine 58.
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic phosphopeptide derived from human Tryptophan Hydroxylase around the phosphorylation site of serine 58 (R-N-SP-E-F).

  • Positive control
    • Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab61068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
IHC-P 1/50 - 1/100.

Target

  • Tissue specificityIsoform 2 seems to be less widely expressed than isoform 1.
  • PathwayAromatic compound metabolism; serotonin biosynthesis; serotonin from L-tryptophan: step 1/2.
  • Sequence similaritiesBelongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    Contains 1 ACT domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • Indoleacetic acid 5 hydroxylase antibody
    • L tryptophan hydroxylase antibody
    • MGC119994 antibody
    • TPH 1 antibody
    • TPH antibody
    • TPH1 antibody
    • TPH1_HUMAN antibody
    • TPRH antibody
    • TRPH antibody
    • Tryptophan 5 hydroxylase 1 antibody
    • Tryptophan 5 monooxygenase 1 antibody
    • Tryptophan 5 monooxygenase antibody
    • Tryptophan 5-hydroxylase 1 antibody
    • Tryptophan 5-monooxygenase 1 antibody
    • Tryptophan hydroxylase 1 antibody
    see all

Anti-Tryptophan Hydroxylase (phospho S58) antibody images

  • Immunohistochemistry analysis of paraffin-embedded human right temporal lobe using ab61068 at 1/50-1/100 dilution with or without immunising phosphopeptide.

References for Anti-Tryptophan Hydroxylase (phospho S58) antibody (ab61068)

ab61068 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Frozen sections)
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C
Sample Zebrafish Tissue sections (heart)
Specification heart
Permeabilization Yes - 0.3% Triton
Fixative Paraformaldehyde
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Submitted Feb 05 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"