Anti-Tryptophanyl tRNA synthetase antibody (ab58054)

Overview

  • Product nameAnti-Tryptophanyl tRNA synthetase antibody
    See all Tryptophanyl tRNA synthetase primary antibodies
  • Description
    Mouse monoclonal to Tryptophanyl tRNA synthetase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: YKAAAGEDYK ADCPPGNPAP TSNHGPDATE AEEDFVDPWT VQTSSAKGID YDKLIVRFGS SKIDKELINR IERATGQRPH HFLRRGIFFS HRDMNQVLDA , corresponding to amino acids 50-150 of Human Tryptophanyl tRNA synthetase

Properties

Applications

Our Abpromise guarantee covers the use of ab58054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionIsoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
    • Sequence similaritiesBelongs to the class-I aminoacyl-tRNA synthetase family.
      Contains 1 WHEP-TRS domain.
    • Post-translational
      modifications
      Proteolytic cleavage generates 2 forms; T1-TrpRS and T2-TrpRS.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Gamma 2 antibody
      • GAMMA-2 antibody
      • Gamma2 antibody
      • hWRS antibody
      • IFI 53 antibody
      • IFI53 antibody
      • IFP 53 antibody
      • IFP53 antibody
      • Interferon induced protein 53 antibody
      • Interferon-induced protein 53 antibody
      • SYWC_HUMAN antibody
      • T2-TrpRS antibody
      • TrpRS antibody
      • Tryptophan tRNA ligase, cytoplasmic antibody
      • Tryptophan tRNA ligase 1 cytoplasmic antibody
      • Tryptophan tRNA ligase antibody
      • Tryptophan--tRNA ligase antibody
      • Tryptophanyl tRNA synthetase antibody
      • Tryptophanyl tRNA synthetase cytoplasmic antibody
      • WARS antibody
      • WARS protein antibody
      • WRS antibody
      see all

    Anti-Tryptophanyl tRNA synthetase antibody images



    • Predicted band size : 53 kDa
      Tryptophanyl tRNA synthetase antibody (ab58054) at 1ug/lane + HeLa cell lysate at 25ug/lane.
    • ab58054 at 10 ug/ml staining Tryptophanyl tRNA synthetase in human Hella cells by Immunocytochemistry/ Immunofluorescence.

    References for Anti-Tryptophanyl tRNA synthetase antibody (ab58054)

    ab58054 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"