Overview

  • Product nameAnti-TSEN34 antibody
  • Description
    Mouse polyclonal to TSEN34
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human TSEN34 protein (AAH00944.1, 390 a.a)

  • Positive control
    • TSEN34 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab68868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 43 kDa).

Target

  • RelevanceTSEN 34 constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron, the first step in tRNA splicing. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
  • Cellular localizationNuclear. nucleolus. Note: May be transiently localized in the nucleolus.
  • Database links
  • Alternative names
    • HsSen34 antibody
    • LENG 5 antibody
    • LENG5 antibody
    • Leukocyte receptor cluster (LRC) member 5 antibody
    • Leukocyte receptor cluster member 5 antibody
    • SEN 34 antibody
    • SEN34 antibody
    • SEN34L antibody
    • tRNA intron endonuclease Sen34 antibody
    • tRNA splicing endonuclease 34 homolog antibody
    • tRNA splicing endonuclease subunit Sen34 antibody
    • TSEN 34 antibody
    see all

Anti-TSEN34 antibody images

  • All lanes : Anti-TSEN34 antibody (ab68868) at 1/500 dilution

    Lane 1 : TSEN34 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 43 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

References for Anti-TSEN34 antibody (ab68868)

ab68868 has not yet been referenced specifically in any publications.

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