Overview

  • Product nameAnti-TSFM antibody
    See all TSFM primary antibodies
  • Description
    Rabbit polyclonal to TSFM
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 128-275 of Human TSFM (P43897).

  • Positive control
    • Jurkat, Raji and K562 whole cell lysates; Gastric cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab125872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 35 kDa.
IHC-P 1/100 - 1/500.

Target

  • FunctionAssociates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
  • Tissue specificityExpressed in all tissues, with the highest levels of expression in skeletal muscle, liver and kidney.
  • Involvement in diseaseDefects in TSFM are the cause of combined oxidative phosphorylation deficiency type 3 (COXPD3) [MIM:610505]. Defects in the mitochondrial oxidative phosphorylation system result in devastating, mainly multisystem, diseases. COXPD3 symptoms include severe metabolic acidosis with encephalomyopathy or with hypertrophic cardiomyopathy. Patients show a severe defect in mitochondrial translation leading to a failure to assemble adequate amounts of three of the oxidative phosphorylation complexes.
  • Sequence similaritiesBelongs to the EF-Ts family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • COXPD 3 antibody
    • COXPD3 antibody
    • EF TS antibody
    • EF Tsmt antibody
    • EF-Ts antibody
    • EF-TsMt antibody
    • EFTS antibody
    • EFTS_HUMAN antibody
    • EFTSMT antibody
    • Elongation factor Ts antibody
    • Elongation factor Ts mitochondrial antibody
    • HGNC12367 antibody
    • mitochondrial antibody
    • Mitochondrial elongation factor Ts antibody
    • Ts translation elongation factor mitochondrial antibody
    • TSFM antibody
    • TSMT antibody
    see all

Anti-TSFM antibody images

  • ab125872, at 1/500, staining TSFM in paraffin-embedded Human gastric cancer tissue by Immunohistochemistry.
  • All lanes : Anti-TSFM antibody (ab125872) at 1/1000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : K562 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 35 kDa

References for Anti-TSFM antibody (ab125872)

ab125872 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125872.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"