Overview

  • Product nameAnti-TSH alpha antibody
    See all TSH alpha primary antibodies
  • Description
    Rabbit polyclonal to TSH alpha
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 81-111 of Human TSH alpha (NP_000726)

  • Positive control
    • HepG2 cell line lysates
  • General notesPrevent freeze-thaw cycles.

Properties

Applications

Our Abpromise guarantee covers the use of ab111428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 13 kDa.

Target

  • RelevanceThyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • CGA antibody
    • FSHA antibody
    • Glycoprotein hormones alpha chain precursor antibody
    • GPHA1 antibody
    • HCG antibody
    • LHA antibody
    • LSH alpha antibody
    • Thyroid Stimulating Hormone antibody
    • Thyrotropin alpha chain antibody
    • TSH alpha antibody
    • TSHA antibody
    • Vanoxerine antibody
    see all

Anti-TSH alpha antibody images

  • Anti-TSH alpha antibody (ab111428) at 1/100 dilution + HepG2 cell lysate at 35 µg

    Predicted band size : 13 kDa

References for Anti-TSH alpha antibody (ab111428)

ab111428 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"