Overview

  • Product name
  • Description
    Goat polyclonal to TSH alpha
  • Specificity
    This antibody recognizes TSH alpha.
  • Tested applications
    Suitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human TSH (pituitary hormone).

Properties

Applications

Our Abpromise guarantee covers the use of ab30842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • Relevance
    Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • CGA antibody
    • FSHA antibody
    • Glycoprotein hormones alpha chain precursor antibody
    • GPHA1 antibody
    • HCG antibody
    • LHA antibody
    • LSH alpha antibody
    • Thyroid Stimulating Hormone antibody
    • Thyrotropin alpha chain antibody
    • TSH alpha antibody
    • TSHA antibody
    • Vanoxerine antibody
    see all

References

ab30842 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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