Overview

  • Product nameAnti-TSH antibody [11E4]
    See all TSH primary antibodies
  • Description
    Mouse monoclonal [11E4] to TSH
  • SpecificityThis antibody specifically recognizes ß-subunit of human TSH.
  • Tested applicationsSuitable for: Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) from human pituitary gland.

  • General notesThis antibody (capture) is ELISA paired with ab6070 (conjugate).

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab6069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA
  • Application notessELISA: Use at an assay dependent dilution.
    Can be paired for ELISA with Mouse monoclonal [7G12] to TSH (ab6070).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • CG ALPHA antibody
      • CGA antibody
      • Chorionic gonadotropin alpha polypeptide antibody
      • FSHA antibody
      • Glycoprotein hormones alpha polypeptide antibody
      • GPHA1 antibody
      • Thyroid stimulating hormone beta subunit antibody
      • Thyrotropin beta subunit antibody
      • TSH beta antibody
      • TSHA antibody
      • TSHB antibody
      see all

    References for Anti-TSH antibody [11E4] (ab6069)

    ab6069 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry.

    The TSH protein ab110682 is purified human protein. So in theory it should be detected by any antibody which will cross react withhuman TSH. Although please make sure the antibody is also tested in the application ...

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    It is definitely my pleasure to help you with these issues. I look forward to hearing how the new product works in your experiments.

    We do not have the specific antigen used to create these products available on our catalog at this time. How...

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    Thank you for your phone call. I am sending you the following discount codes for trying the antibodies in sELISA and mouse/rat. As for the proteins, I have found the following:

    Luteinizing Hormone: none
    FSH: ab51888 (human) - test in sEL...

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    Thank you for your call this morning and for your patience.

    There is an error on the pdf form of our sandwich ELISA protocol, and the carbonate buffer should be around 9.6. I've looked through several protocols, and most recommend either a pH...

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    Thank you for contacting us.

    I have have the chance to look over each of the TSH ELISA kits. Unfortunately it appears that none of the currently offered kits uses ab6069 or ab24921. It may be that the particular product that was recommended t...

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    Our antibody ab24921 does not react with LH, FSH or HCG, however it is unclear which subunit of the TSH protein this antibody is directed against. On the other hand we do know that ab6069 is specific to the beta subunit of TSH but there is no further i...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"