Overview

  • Product name
  • Description
    Rabbit polyclonal to TSH
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human TSH

  • Positive control
    • Human anterior pituitary tissue
  • General notes
    Cytoplasmic staining pattern

Properties

Applications

Our Abpromise guarantee covers the use of ab64378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200.

Target

  • Relevance
    Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • CG ALPHA antibody
    • CGA antibody
    • Chorionic gonadotropin alpha polypeptide antibody
    • FSHA antibody
    • Glycoprotein hormones alpha polypeptide antibody
    • GPHA1 antibody
    • Thyroid stimulating hormone beta subunit antibody
    • Thyrotropin beta subunit antibody
    • TSH beta antibody
    • TSHA antibody
    • TSHB antibody
    see all

Anti-TSH antibody images

  • ab64378, at a dilution of 1/200, staining TSH in formalin fixed, paraffin embedded human anterior pituitary tissue by Immunohistochemistry.

References for Anti-TSH antibody (ab64378)

This product has been referenced in:
  • Mathioudakis N  et al. Expression of the pituitary stem/progenitor marker GFRa2 in human pituitary adenomas and normal pituitary. Pituitary 18:31-41 (2015). Read more (PubMed: 24402129) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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