Overview

  • Product name
  • Description
    Rabbit polyclonal to TSPAN12
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the C-terminal region of Human TSPAN12 (NP_036470.1).

  • Positive control
    • T47D cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab93179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 35 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      TSPAN12 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a regulator of cell surface receptor signal transduction and plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. It acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. It also acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. It activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP) and activates MMP14/MT1-MMP-dependent cleavage activity.
    • Cellular localization
      Cell membrane; Multi-pass membrane protein.
    • Database links
    • Alternative names
      • 9030619E17 antibody
      • AI426782 antibody
      • AI663988 antibody
      • AW111457 antibody
      • MGC109305 antibody
      • NET 2 antibody
      • NET2 antibody
      • OTTHUMP00000211224 antibody
      • Tetraspan NET 2 antibody
      • Tetraspanin 12 antibody
      • Tetraspanin12 antibody
      • TM4SF12 antibody
      • Transmembrane 4 superfamily member 12 antibody
      • TSPAN 12 antibody
      see all

    Images

    • Anti-TSPAN12 antibody (ab93179) at 1/100 dilution + T47D cell line lysate at 35 µg

      Predicted band size : 35 kDa

    References

    ab93179 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab93179.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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