Overview

  • Product nameAnti-TSSK2 antibody
    See all TSSK2 primary antibodies
  • Description
    Rabbit polyclonal to TSSK2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 251-300 (RMLQPDVSQR LHIDEILSHS WLQPPKPKAT SSASFKREGE GKYRAECKLD) of Human TSSK2 (NP_443732).

  • Positive control
    • NCI-H226 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionTestis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
  • Tissue specificityTestis-specific. Present in mature spermatozoa (at protein level).
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton > centrosome > centriole. Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment (By similarity). In spermatids, concentrates in centrioles during flagellogenesis.
  • Information by UniProt
  • Database links
  • Alternative names
    • DGS-G antibody
    • DGSG antibody
    • DiGeorge syndrome protein G antibody
    • Serine/threonine kinase 22B (spermiogenesis associated) antibody
    • Serine/threonine protein kinase 22B antibody
    • Serine/threonine-protein kinase 22B antibody
    • Spermiogenesis associated 2 antibody
    • SPOGA2 antibody
    • STK22B antibody
    • Testis specific kinase 2 antibody
    • Testis specific serine kinase 2 antibody
    • Testis specific serine threonine kinase 2 antibody
    • Testis specific serine/threonine protein kinase 2 antibody
    • Testis-specific kinase 2 antibody
    • Testis-specific serine/threonine-protein kinase 2 antibody
    • TSK 2 antibody
    • TSK-2 antibody
    • TSK2 antibody
    • TSSK 2 antibody
    • TSSK-2 antibody
    • Tssk2 antibody
    • TSSK2_HUMAN antibody
    see all

Anti-TSSK2 antibody images

  • Anti-TSSK2 antibody (ab98051) at 1 µg/ml (in 5% skim milk / PBS buffer) + NCI-H226 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 41 kDa

References for Anti-TSSK2 antibody (ab98051)

ab98051 has not yet been referenced specifically in any publications.

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