Overview

  • Product nameAnti-TTC11 antibody
    See all TTC11 primary antibodies
  • Description
    Rabbit polyclonal to TTC11
  • Specificityab24242 reacts with Fis1 protein.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide:

    vedllkfekkfqsek

    , corresponding to amino acids 11-25 of Human TTC11

Properties

Applications

Our Abpromise guarantee covers the use of ab24242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 17 kDa.

Target

  • FunctionPromotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
  • Sequence similaritiesBelongs to the FIS1 family.
    Contains 1 TPR repeat.
  • DomainThe C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
  • Post-translational
    modifications
    Ubiquitinated by MARCH5.
  • Cellular localizationMitochondrion outer membrane. Peroxisome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2010003O14Rik antibody
    • CGI 135 antibody
    • CGI135 antibody
    • FIS 1 antibody
    • FIS1 antibody
    • Fis1 homolog antibody
    • FIS1, S. cerevisiae, homolog of antibody
    • FIS1_HUMAN antibody
    • Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) antibody
    • Fission 1 (mitochondrial outer membrane) homolog (yeast) antibody
    • Fission 1 (mitochondrial outer membrane) homolog antibody
    • Fission 1 homolog antibody
    • H NH0132A01.6 antibody
    • hFis 1 antibody
    • hFis1 antibody
    • Mitochondrial fission 1 protein antibody
    • Tetratricopeptide repeat domain 11 antibody
    • Tetratricopeptide repeat protein 11 antibody
    • TPR repeat protein 11 antibody
    • TTC 11 antibody
    see all

References for Anti-TTC11 antibody (ab24242)

This product has been referenced in:
  • Winden KD  et al. The organization of the transcriptional network in specific neuronal classes. Mol Syst Biol 5:291 (2009). WB ; Mouse . Read more (PubMed: 19638972) »

See 1 Publication for this product

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The protein sequence of human Fis1 (http://www.uniprot.org/uniprot/Q9Y3D6) and Saccharomyces (http://www.uniprot.org/uniprot/P40515) do not match (http://www.ebi.ac.uk/Tools/services/web_clustalw2/toolresult.ebi?to...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"