Anti-TTC11 antibody - N-terminal (ab189846)

Overview

  • Product name
    Anti-TTC11 antibody - N-terminal
    See all TTC11 primary antibodies
  • Description
    Rabbit polyclonal to TTC11 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow
  • Immunogen

    Recombinant full length protein corresponding to Human TTC11 aa 1-122 (N terminal).
    Sequence:

    MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG


    Database link: Q9Y3D6

  • Positive control
    • 293T, HepG2, A549, HeLa, MCF7, Mouse spleen and Mouse kidney cell line extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab189846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 17 kDa.
IHC-P 1/50 - 1/200.

Target

  • Function
    Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
  • Sequence similarities
    Belongs to the FIS1 family.
    Contains 1 TPR repeat.
  • Domain
    The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
  • Post-translational
    modifications
    Ubiquitinated by MARCH5.
  • Cellular localization
    Mitochondrion outer membrane. Peroxisome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2010003O14Rik antibody
    • CGI 135 antibody
    • CGI135 antibody
    • FIS 1 antibody
    • FIS1 antibody
    • Fis1 homolog antibody
    • FIS1, S. cerevisiae, homolog of antibody
    • FIS1_HUMAN antibody
    • Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) antibody
    • Fission 1 (mitochondrial outer membrane) homolog (yeast) antibody
    • Fission 1 (mitochondrial outer membrane) homolog antibody
    • Fission 1 homolog antibody
    • H NH0132A01.6 antibody
    • hFis 1 antibody
    • hFis1 antibody
    • Mitochondrial fission 1 protein antibody
    • mitochondrial fission molecule antibody
    • Tetratricopeptide repeat domain 11 antibody
    • Tetratricopeptide repeat protein 11 antibody
    • TPR repeat protein 11 antibody
    • TTC 11 antibody
    see all

Images

  • All lanes : Anti-TTC11 antibody - N-terminal (ab189846) at 1/500 dilution

    Lane 1 : 293T cell line extract
    Lane 2 : HepG2 cell line extract
    Lane 3 : A549 cell line extract
    Lane 4 : HeLa cell line extract
    Lane 5 : MCF7 cell line extract
    Lane 6 : Mouse spleen cell line extract
    Lane 7 : Mouse kidney cell line extract

    Predicted band size: 17 kDa

References

ab189846 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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