Overview

  • Product name
  • Description
    Rabbit polyclonal to TTC21B
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: ALAHEPVNEL SALMEDGRCQ VLLAKVYSKM EKLGDAITAL QQARELQARV LKRVQMEQPD AVPAQKHLAA EICAEIAKHS VAQRDYE, corresponding to amino acids 815-901 of Human TTC21B.

  • Positive control
    • U251-MG cell lysate; Human colon tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab122282 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000.
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May negatively modulate SHH signal transduction and may play a role in retrograde intraflagellar transport in cilia.
  • Sequence similarities
    Belongs to the TTC21 family.
    Contains 19 TPR repeats.
  • Cellular localization
    Cytoplasm > cytoskeleton > cilium axoneme.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATD4 antibody
    • IFT139 antibody
    • JBTS11 antibody
    • Nbla10696 antibody
    • NPHP12 antibody
    • Putative protein product of Nbla10696 antibody
    • SRTD4 antibody
    • Tetratricopeptide repeat protein 21B antibody
    • THM1 antibody
    • TPR repeat protein 21B antibody
    • TT21B_HUMAN antibody
    • Ttc21b antibody
    see all

Images

  • All lanes : Anti-TTC21B antibody (ab122282) at 1/250 dilution

    Lane 1 : RT-4 cell lysate
    Lane 2 : U251-MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique
  • ab122282, at 1/350 dilution, staining TTC21B in paraffin-embedded Human colon tissue by Immunohistochemistry.

References

ab122282 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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