• Product nameAnti-TUBA6 antibody
    See all TUBA6 primary antibodies
  • Description
    Rabbit polyclonal to TUBA6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 421-449 of Human TUBA6 (NP_116093.1)

  • Positive control
    • K562 cell line lysates.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab110810 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab110810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.


  • FunctionTubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
  • Sequence similaritiesBelongs to the tubulin family.
  • Post-translational
    Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.
    Some glutamate residues at the C-terminus are polyglutamylated. This modification occurs exclusively on glutamate residues and results in polyglutamate chains on the gamma-carboxyl group. Also monoglycylated but not polyglycylated due to the absence of functional TTLL10 in human. Monoglycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering glycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they regulate the assembly and dynamics of axonemal microtubules.
    Acetylation of alpha-tubulins at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha tubulin 6 antibody
    • Alpha tubulin isotype M alpha 6 antibody
    • Alpha-tubulin 6 antibody
    • bcm948 antibody
    • M[a]6 antibody
    • TBA1C_HUMAN antibody
    • Tuba1c antibody
    • Tubulin alpha 1C chain antibody
    • tubulin alpha 6 antibody
    • Tubulin alpha 6 chain antibody
    • Tubulin alpha-1C chain antibody
    • Tubulin alpha-6 chain antibody
    • tubulin, alpha 1c antibody
    see all

Anti-TUBA6 antibody images

  • Anti-TUBA6 antibody (ab110810) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 50 kDa

References for Anti-TUBA6 antibody (ab110810)

ab110810 has not yet been referenced specifically in any publications.

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