Anti-Tubulin Polymerization Promoting Protein antibody (ab117948)

Overview

  • Product nameAnti-Tubulin Polymerization Promoting Protein antibody
    See all Tubulin Polymerization Promoting Protein primary antibodies
  • Description
    Rabbit polyclonal to Tubulin Polymerization Promoting Protein
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chicken, Guinea pig, Cat, Dog
  • Immunogen

    Synthetic peptide, corresponding to a region within N terminal amino acids 17-66 (KSPGDPSKDR AAKRLSLESE GAGEGAAASP ELSALEEAFR RFAVHGDARA) of Human Tubulin Polymerization Promoting Protein (NP_008961).

  • Positive control
    • Human fetal liver lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab117948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the TPPP family.
  • Post-translational
    modifications
    Poor substrate for GSK3 (By similarity). Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity.
  • Cellular localizationCytoplasm. Cytoplasm, cytoskeleton. Nucleus. Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies.
  • Information by UniProt
  • Database links
  • Alternative names
    • 25 kDa brain specific protein antibody
    • 25 kDa brain-specific protein antibody
    • Brain specific protein p25 alpha antibody
    • Glycogen synthase kinase 3 (GSK3) inhibitor p24 antibody
    • OTTHUMP00000161630 antibody
    • p24 antibody
    • p25 antibody
    • p25-alpha antibody
    • p25alpha antibody
    • TPPP antibody
    • TPPP/p25 antibody
    • TPPP_HUMAN antibody
    • TPPP1 antibody
    • Tubulin polymerization promoting protein antibody
    • Tubulin polymerization-promoting protein antibody
    see all

Anti-Tubulin Polymerization Promoting Protein antibody images

  • Anti-Tubulin Polymerization Promoting Protein antibody (ab117948) at 1 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 23 kDa

References for Anti-Tubulin Polymerization Promoting Protein antibody (ab117948)

ab117948 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab117948.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"