Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] (ab119987)


  • Product nameAnti-Tubulin Polymerization Promoting Protein antibody [EPR3315]
    See all Tubulin Polymerization Promoting Protein primary antibodies
  • Description
    Rabbit monoclonal [EPR3315] to Tubulin Polymerization Promoting Protein
  • Tested applicationsSuitable for: WB, IHC-P, IPmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human Tubulin Polymerization Promoting Protein.

  • Positive control
    • Human fetal brain and SH-SY5Y cell lysates; Human astrocytoma tissue.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab119987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 25 kDa (predicted molecular weight: 23 kDa).
IHC-P 1/100 - 1/250. Antigen retrieval is recommended. Heat up to 98 °C, below boiling, and then let cool for 10-20 min.
IP 1/10 - 1/100.
  • Application notesIs unsuitable for Flow Cyt or ICC.
  • Target

    • FunctionMay play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
    • Tissue specificityWidely expressed.
    • Sequence similaritiesBelongs to the TPPP family.
    • Post-translational
      Poor substrate for GSK3 (By similarity). Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity.
    • Cellular localizationCytoplasm. Cytoplasm, cytoskeleton. Nucleus. Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies.
    • Information by UniProt
    • Database links
    • Alternative names
      • 25 kDa brain specific protein antibody
      • 25 kDa brain-specific protein antibody
      • Brain specific protein p25 alpha antibody
      • Glycogen synthase kinase 3 (GSK3) inhibitor p24 antibody
      • OTTHUMP00000161630 antibody
      • p24 antibody
      • p25 antibody
      • p25-alpha antibody
      • p25alpha antibody
      • TPPP antibody
      • TPPP/p25 antibody
      • TPPP_HUMAN antibody
      • TPPP1 antibody
      • Tubulin polymerization promoting protein antibody
      • Tubulin polymerization-promoting protein antibody
      see all

    Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] images

    • All lanes : Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] (ab119987) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : SH-SY5Y cell lysate

      Lysates/proteins at 10 µg per lane.

      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 23 kDa
    • ab119987 at 1/100 dilution staining Tubulin Polymerization Promoting Protein in Paraffin-embedded Human astrocytoma tissue by Immunohistochemistry.

    References for Anti-Tubulin Polymerization Promoting Protein antibody [EPR3315] (ab119987)

    ab119987 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab119987.
    Please use the links above to contact us or submit feedback about this product.