Overview

  • Product nameAnti-TUG antibody
    See all TUG primary antibodies
  • Description
    Rabbit polyclonal to TUG
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region between amino acids 175-225 of Human TUG (NP_076988.1).

  • Positive control
    • HeLa whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab114980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionTethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.
    • Tissue specificityUbiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.
    • Involvement in diseaseNote=A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.
      Note=A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).
    • Sequence similaritiesContains 1 UBX domain.
    • Cellular localizationEndomembrane system.
    • Information by UniProt
    • Database links
    • Alternative names
      • Alveolar soft part sarcoma chromosomal region candidate gene 1 protein antibody
      • Alveolar soft part sarcoma chromosome region candidate 1 (human) antibody
      • Alveolar soft part sarcoma locus antibody
      • ASPC antibody
      • ASPC1_HUMAN antibody
      • ASPCR 1 antibody
      • ASPCR1 antibody
      • ASPL antibody
      • ASPS antibody
      • ASPSCR 1 antibody
      • Aspscr1 antibody
      • FLJ45380 antibody
      • RCC 17 antibody
      • RCC17 antibody
      • renal cell carcinoma gene on chromosome 17 antibody
      • renal cell carcinoma papillary 17 antibody
      • Renal papillary cell carcinoma protein 17 antibody
      • Tether containing a UBX domain for GLUT4 antibody
      • Tether containing UBX domain for GLUT4 antibody
      • TUG antibody
      • UBX domain containing protein 9 antibody
      • UBX domain protein 9 antibody
      • UBX domain-containing protein 9 antibody
      • UBXD 9 antibody
      • UBXD9 antibody
      • UBXN 9 antibody
      • UBXN9 antibody
      see all

    Anti-TUG antibody images

    • Detection of TUG in Immunoprecipitates of HeLa whole cell lysates (1 mg for IP, 20% of IP loaded) using ab114980 at 3 µg/mg lysate for IP. For WB detection an anti-TUG antibody which recognizes a downstream epitope was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

    References for Anti-TUG antibody (ab114980)

    ab114980 has not yet been referenced specifically in any publications.

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