Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab123382 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 70-75 kDa (predicted molecular weight: 60 kDa).

Target

  • Function
    Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.
  • Tissue specificity
    Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.
  • Involvement in disease
    Note=A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.
    Note=A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).
  • Sequence similarities
    Contains 1 UBX domain.
  • Cellular localization
    Endomembrane system.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alveolar soft part sarcoma chromosomal region candidate gene 1 protein antibody
    • Alveolar soft part sarcoma chromosome region candidate 1 (human) antibody
    • Alveolar soft part sarcoma locus antibody
    • ASPC antibody
    • ASPC1_HUMAN antibody
    • ASPCR 1 antibody
    • ASPCR1 antibody
    • ASPL antibody
    • ASPS antibody
    • ASPSCR 1 antibody
    • Aspscr1 antibody
    • FLJ45380 antibody
    • RCC 17 antibody
    • RCC17 antibody
    • renal cell carcinoma gene on chromosome 17 antibody
    • renal cell carcinoma papillary 17 antibody
    • Renal papillary cell carcinoma protein 17 antibody
    • Tether containing a UBX domain for GLUT4 antibody
    • Tether containing UBX domain for GLUT4 antibody
    • TUG antibody
    • UBX domain containing protein 9 antibody
    • UBX domain protein 9 antibody
    • UBX domain-containing protein 9 antibody
    • UBXD 9 antibody
    • UBXD9 antibody
    • UBXN 9 antibody
    • UBXN9 antibody
    see all

Images

  • Anti-TUG antibody (ab123382) at 1/500 dilution + HL60 cell extract

    Predicted band size : 60 kDa

References

ab123382 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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