Overview

  • Product name
  • Description
    Rabbit polyclonal to TULP3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 129 - 403 of Human TULP3 (Uniprot ID O75386)

  • Positive control
    • HepG2 cell lysate and Raji cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab155317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 50 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Negatively regulates SHH signal transduction (By similarity). Probably functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to phosphorylated inositide lipids.
  • Tissue specificity
    Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
  • Sequence similarities
    Belongs to the TUB family.
  • Cellular localization
    Nucleus. Cell membrane. Cell projection > cilium. Cytoplasm. Secreted. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC45295 antibody
    • Tubby like protein 3 antibody
    • Tubby related protein 3 antibody
    • Tubby-like protein 3 antibody
    • Tubby-related protein 3 antibody
    • TUBL 3 antibody
    • TUBL3 antibody
    • TULP 3 antibody
    • TULP3 antibody
    • TULP3_HUMAN antibody
    see all

Images

  • Anti-TULP3 antibody (ab155317) at 1/1000 dilution + HepG2 cell lysate at 30 µg

    Predicted band size: 50 kDa



    10% SDS PAGE
  • Immunofluorescence of methanol-fixed HepG2 cells labeling TULPC using ab155317 at 1/200 dilution. Lower image shows cells co-stained with Hoechst 33342.

References

ab155317 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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