Overview

  • Product name
  • Description
    Mouse polyclonal to TULP3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length TULP3 protein (Human)

  • Positive control
    • TULP3 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab67624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 50 kDa).

Target

  • Function
    Negatively regulates SHH signal transduction (By similarity). Probably functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to phosphorylated inositide lipids.
  • Tissue specificity
    Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
  • Sequence similarities
    Belongs to the TUB family.
  • Cellular localization
    Nucleus. Cell membrane. Cell projection > cilium. Cytoplasm. Secreted. Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC45295 antibody
    • Tubby like protein 3 antibody
    • Tubby related protein 3 antibody
    • Tubby-like protein 3 antibody
    • Tubby-related protein 3 antibody
    • TUBL 3 antibody
    • TUBL3 antibody
    • TULP 3 antibody
    • TULP3 antibody
    • TULP3_HUMAN antibody
    see all

Images

  • All lanes : Anti-TULP3 antibody (ab67624) at 1/500 dilution

    Lane 1 : TULP3 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 50 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

References

ab67624 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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