Overview

  • Product nameTunicamycin
  • Description
    Antibiotic. Protein glycosylation inhibitor.
  • Biological descriptionNucleoside antibiotic that inhibits protein glycosylation. Inhibits GlcNAc phosphotransferase (GPT) and inhibits the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first step of glycoprotein synthesis. Inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi and viruses.
  • Purity> 98%
  • General notes

    This compound is a mixture of the homologs of tunicamycin: A, B, C and D which vary in the carbon chain length (n=8 to 11)

Properties

    Applications

    Our Abpromise guarantee covers the use of ab120296 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    References for Tunicamycin (ab120296)

    This product has been referenced in:

    See 1 Publication for this product

    Product Wall

    Thank you very much for your call last week and for your patience while I have been in touch with our biochemical scientists regarding your enquiry.

    We quote solubility in DMSO of 50mM and believe it's quite easily dissolved at room temperatu...

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