Overview

  • Product name
    Tunicamycin
  • Description
    Antibiotic. Protein glycosylation inhibitor.
  • Biological description
    Nucleoside antibiotic that inhibits protein glycosylation. Inhibits GlcNAc phosphotransferase (GPT) and inhibits the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first step of glycoprotein synthesis. Inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi and viruses.
  • Purity
    > 98%
  • General notes

    This compound is a mixture of the homologs of tunicamycin: A, B, C and D which vary in the carbon chain length (n=8 to 11)

Properties

Applications

Our Abpromise guarantee covers the use of ab120296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.

References

This product has been referenced in:

See all 2 Publications for this product

Customer reviews and Q&As

Thank you very much for your call last week and for your patience while I have been in touch with our biochemical scientists regarding your enquiry.

We quote solubility in DMSO of 50mM and believe it's quite easily dissolved at room temperatu...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up