Overview

  • Product nameAnti-TUSC2 antibody
    See all TUSC2 primary antibodies
  • Description
    Rabbit polyclonal to TUSC2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide derived from an internal region of human TUSC2.

  • Positive control
    • extracts from HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab70182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately >19 kDa (predicted molecular weight: 12 kDa).
ELISA 1/5000.

Target

  • FunctionMay function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.
  • Tissue specificityStrong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
  • Sequence similaritiesBelongs to the TUSC2 family.
  • Post-translational
    modifications
    Myristoylation is required for tumor suppressor activity.
  • Information by UniProt
  • Database links
  • Alternative names
    • C3orf11 antibody
    • Fus-1 protein antibody
    • FUS1 antibody
    • Fusion 1 protein antibody
    • LGCC antibody
    • PAP antibody
    • PDAP2 antibody
    • PDGFA associated protein 2 antibody
    • PDGFA-associated protein 2 antibody
    • Tumor suppressor candidate 2 antibody
    • TUSC 2 antibody
    • Tusc2 antibody
    • TUSC2_HUMAN antibody
    see all

Anti-TUSC2 antibody images

  • All lanes : Anti-TUSC2 antibody (ab70182) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : HeLa cell extract with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 12 kDa
    Observed band size : <19 kDa (why is the actual band size different from the predicted?)

References for Anti-TUSC2 antibody (ab70182)

This product has been referenced in:
  • Rutnam ZJ  et al. The pseudogene TUSC2P promotes TUSC2 function by binding multiple microRNAs. Nat Commun 5:2914 (2014). WB ; Mouse . Read more (PubMed: 24394498) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab70182.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"