Overview

  • Product nameAnti-TWEAK antibody
    See all TWEAK primary antibodies
  • Description
    Mouse monoclonal to TWEAK
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: SLSAQEPAQE ELVAEEDQDP SELNPQTEES QDPAPFLNRL VRPRRSAPKG RKTRARRAIA AHYEVHPRPG QDGAQADGGY TTCLRP, corresponding to amino acids 49-135 of Human TWEAK

Properties

Applications

Our Abpromise guarantee covers the use of ab57926 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
    • Tissue specificityHighly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
    • Sequence similaritiesBelongs to the tumor necrosis factor family.
    • Post-translational
      modifications
      The soluble form derives from the membrane form by proteolytic processing.
    • Cellular localizationSecreted and Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • APO 3 ligand antibody
      • APO 3L antibody
      • APO3 ligand antibody
      • APO3/DR3 ligand antibody
      • APO3L antibody
      • DR3LG antibody
      • MGC129581 antibody
      • MGC20669 antibody
      • secreted form antibody
      • TNF-related weak inducer of apoptosis antibody
      • TNF12_HUMAN antibody
      • TNFSF 12 antibody
      • Tnfsf12 antibody
      • TNFSF12 protein antibody
      • Tumor necrosis factor (ligand) superfamily member 12 antibody
      • Tumor necrosis factor ligand superfamily member 12 antibody
      • Tumor necrosis factor superfamily member 12 antibody
      • TWEAK antibody
      • UNQ181/PRO207 antibody
      see all

    Anti-TWEAK antibody images

    • Western blot against tagged recombinant protein immunogen using ab57926 TWEAK antibody at 1ug/ml. Predicted band size of immunogen is 33 kDa

    References for Anti-TWEAK antibody (ab57926)

    ab57926 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57926.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"