Overview

  • Product nameAnti-TWEAK antibody (Biotin)
    See all TWEAK primary antibodies
  • Description
    Goat polyclonal to TWEAK (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant human TWEAK.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab83437 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
WB
  • Application notesELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human TWEAK.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human TWEAK.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human TWEAK is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. Predicted molecular weight: 27 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
    • Tissue specificityHighly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
    • Sequence similaritiesBelongs to the tumor necrosis factor family.
    • Post-translational
      modifications
      The soluble form derives from the membrane form by proteolytic processing.
    • Cellular localizationSecreted and Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • APO 3 ligand antibody
      • APO 3L antibody
      • APO3 ligand antibody
      • APO3/DR3 ligand antibody
      • APO3L antibody
      • DR3LG antibody
      • MGC129581 antibody
      • MGC20669 antibody
      • secreted form antibody
      • TNF-related weak inducer of apoptosis antibody
      • TNF12_HUMAN antibody
      • TNFSF 12 antibody
      • Tnfsf12 antibody
      • TNFSF12 protein antibody
      • Tumor necrosis factor (ligand) superfamily member 12 antibody
      • Tumor necrosis factor ligand superfamily member 12 antibody
      • Tumor necrosis factor superfamily member 12 antibody
      • TWEAK antibody
      • UNQ181/PRO207 antibody
      see all

    References for Anti-TWEAK antibody (Biotin) (ab83437)

    ab83437 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab83437.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"