Anti-Twist antibody [Twist2C1a] - ChIP Grade (ab50887)

ab50887 has been referenced in 82 publications.

• Ito N  et al. Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency. Sci Rep 8:1634 (2018). PubMed: 29374279
• Puglisi R  et al. SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma. Oncotarget 9:7567-7581 (2018). PubMed: 29484133
• Qiao W  et al. Prognostic and clinicopathological value of Twist expression in breast cancer: A meta-analysis. PLoS One 12:e0186191 (2017). PubMed: 29016671
• Yang RM  et al. miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis. Cell Death Dis 8:e3129 (2017). WB . PubMed: 29048402
• Ihira K  et al. EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis. Oncotarget : (2017). WB . PubMed: 28088786
• Bouard C  et al. Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach. BMC Struct Biol 17:6 (2017). PubMed: 28521820
• Wang C  et al. Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/ß-catenin signaling pathways in hepatocellular and colorectal carcinoma cells. Oncotarget 8:1092-1109 (2017). WB ; Human . PubMed: 27901475
• Wang T  et al. Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/ß-catenin signaling pathway. Oncotarget 8:18991-19012 (2017). WB ; Human . PubMed: 28177909
• Xiong H  et al. Twist1 Enhances Hypoxia Induced Radioresistance in Cervical Cancer Cells by Promoting Nuclear EGFR Localization. J Cancer 8:345-353 (2017). WB, ICC/IF ; Human . PubMed: 28261334
• Luan X  et al. HMGB1 is negatively correlated with the development of endometrial carcinoma and prevents cancer cell invasion and metastasis by inhibiting the process of epithelial-to-mesenchymal transition. Onco Targets Ther 10:1389-1402 (2017). PubMed: 28424555
• Wang S  et al. Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/ß-catenin signaling pathway. Sci Rep 7:6215 (2017). PubMed: 28740094
• Khoshgoo N  et al. MicroRNA-200b regulates distal airway development by maintaining epithelial integrity. Sci Rep 7:6382 (2017). PubMed: 28743913
• Zhang D  et al. Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway. Int J Oncol 50:1513-1530 (2017). WB ; Human . PubMed: 28339091
• Opinto G  et al. Hierarchical clustering analysis identifies metastatic colorectal cancers patients with more aggressive phenotype. Oncotarget 8:87782-87794 (2017). IHC-P ; Human . PubMed: 29152120
• Samaranayake GJ  et al. Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer. Nat Commun 8:1204 (2017). PubMed: 29089489
• Yang J  et al. HIF-2a promotes the formation of vasculogenic mimicry in pancreatic cancer by regulating the binding of Twist1 to the VE-cadherin promoter. Oncotarget 8:47801-47815 (2017). PubMed: 28599281
• Kim YH  et al. Senescent tumor cells lead the collective invasion in thyroid cancer. Nat Commun 8:15208 (2017). IHC . PubMed: 28489070
• Dongre A  et al. Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas. Cancer Res 77:3982-3989 (2017). WB . PubMed: 28428275
• Lee YS  et al. Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways. Oncotarget 7:36842-36853 (2016). WB . PubMed: 27167205
• Wei C  et al. Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein. Sci Rep 6:29822 (2016). IHC-P ; Human . PubMed: 27412325
• Krstic M  et al. The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer. BMC Cancer 16:671 (2016). WB ; Human . PubMed: 27553211
• Ito M  et al. Evaluation of aldehyde dehydrogenase 1 and transcription factors in both primary breast cancer and axillary lymph node metastases as a prognostic factor. Breast Cancer 23:437-44 (2016). PubMed: 25599843
• Cho MS  et al. Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial-Mesenchymal Transition. J Immunol 196:1412-8 (2016). PubMed: 26718342
• Kim MS  et al. Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer. Sci Rep 6:33899 (2016). WB . PubMed: 27654855
• Bildsoe H  et al. Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest. Data Brief 9:372-375 (2016). ChIP . PubMed: 27699189
• Wu SY  et al. A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. Nat Commun 7:11169 (2016). ChIP ; Human . PubMed: 27041221
• Bouard C  et al. Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences. Nucleic Acids Res 44:5470-89 (2016). WB ; Human . PubMed: 27151200
• Sun X  et al. MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist. J Exp Clin Cancer Res 35:10 (2016). WB ; Human . PubMed: 26762267
• Sun T  et al. The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation. J Biol Chem 291:11518-28 (2016). PubMed: 26975371
• Chen D  et al. MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1a-TWIST signaling axis in breast cancer. Oncotarget 6:32701-12 (2015). PubMed: 26196741
• Grzegrzolka J  et al. Expression of EMT Markers SLUG and TWIST in Breast Cancer. Anticancer Res 35:3961-8 (2015). Human . PubMed: 26124343
• Wei SC  et al. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nat Cell Biol 17:678-88 (2015). ICC/IF ; Human . PubMed: 25893917
• Zheng S  et al. Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators. J Immunol 195:217-26 (2015). WB, ChIP ; Human . PubMed: 26019273
• Mego M  et al. Relationship between circulating tumor cells and epithelial to mesenchymal transition in early breast cancer. BMC Cancer 15:533 (2015). IHC-P ; Human . PubMed: 26194471
• Meier D  et al. Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes. PLoS One 10:e0137229 (2015). ChIP . PubMed: 26361389
• Piskareva O  et al. The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro. Cancer Lett N/A:N/A (2015). PubMed: 25960282
• Benzoubir N  et al. Gamma-smooth muscle actin expression is associated with epithelial-mesenchymal transition and stem-like properties in hepatocellular carcinoma. PLoS One 10:e0130559 (2015). Human . PubMed: 26110787
• Nordfors K  et al. Twist predicts poor outcome of patients with astrocytic glioma. J Clin Pathol 68:905-12 (2015). Human . PubMed: 26163539
• Zhao L  et al. Bufalin inhibits TGF-ß-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-ß receptors. Int J Mol Med : (2015). Human . PubMed: 26133118
• Li J  et al. Endothelial TWIST1 promotes pathological ocular angiogenesis. Invest Ophthalmol Vis Sci 55:8267-77 (2014). IHC ; Mouse . PubMed: 25414194
• Fukai J  et al. Intracranial extension of adenoid cystic carcinoma: potential involvement of EphA2 expression and epithelial-mesenchymal transition in tumor metastasis: a case report. BMC Res Notes 7:131 (2014). Human . PubMed: 24606764
• Xu Y  et al. SRC-1 and Twist1 expression positively correlates with a poor prognosis in human breast cancer. Int J Biol Sci 10:396-403 (2014). IHC ; Human . PubMed: 24719557
• Li A  et al. Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes. Gastroenterology 146:1386-96.e1-17 (2014). WB, ICC/IF ; Mouse . PubMed: 24462734
• Loebel DA  et al. Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterning. PLoS One 9:e98945 (2014). ICC/IF ; Mouse . PubMed: 24893291
• Qiang L  et al. Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A 111:9241-6 (2014). PubMed: 24927592
• Zhang P  et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol 16:864-75 (2014). PubMed: 25086746
• D'Angelo RC  et al. TIMP-1 via TWIST1 induces EMT phenotypes in human breast epithelial cells. Mol Cancer Res 12:1324-33 (2014). Human . PubMed: 24895412
• Lu H  et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol 16:1105-17 (2014). PubMed: 25266422
• Bai F  et al. BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development. Cancer Res 74:6161-72 (2014). PubMed: 25239453
• Goodwin JM  et al. An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Mol Cell 55:436-50 (2014). PubMed: 25042806
• Wushou A  et al. Twist-1 up-regulation in carcinoma correlates to poor survival. Int J Mol Sci 15:21621-30 (2014). PubMed: 25429425
• Zhu DY  et al. Twist1 correlates with poor differentiation and progression in gastric adenocarcinoma via elevation of FGFR2 expression. World J Gastroenterol 20:18306-15 (2014). Human . PubMed: 25561797
• Bernard JJ  et al. Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells. J Carcinog Mutagen 5:2157-2518 (2014). WB ; Mouse . PubMed: 25821644
• Bai Y  et al. Bmp signaling represses Vegfa to promote outflow tract cushion development. Development 140:3395-402 (2013). IHC-P ; Mouse . PubMed: 23863481
• Liang YJ  et al. MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer. Carcinogenesis 34:713-22 (2013). WB ; Human . PubMed: 23250910
• Chu IM  et al. Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß. PLoS One 8:e61125 (2013). WB . PubMed: 23577196
• Malaquin N  et al. Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis. PLoS One 8:e63607 (2013). WB ; Human . PubMed: 23675494
• Xu Y  et al. Inducible knockout of twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting twist1 as a preferential cancer target. Am J Pathol 183:1281-92 (2013). PubMed: 23906809
• Toll A  et al. Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases. J Dermatol Sci 72:93-102 (2013). PubMed: 23928229
• Stewart CA  et al. CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development. Mol Endocrinol 27:1442-54 (2013). PubMed: 23904126
• Arumugam A  et al. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PLoS One 8:e80076 (2013). Human . PubMed: 24260338
• Dong P  et al. Identification of KLF17 as a novel epithelial to mesenchymal transition inducer via direct activation of TWIST1 in endometrioid endometrial cancer. Carcinogenesis N/A:N/A (2013). PubMed: 24220291
• Das RK  et al. Epithelio-mesenchymal transitional attributes in oral sub-mucous fibrosis. Exp Mol Pathol 95:259-69 (2013). IHC-P ; Human . PubMed: 23994666
• van Nes JG  et al. Co-expression of SNAIL and TWIST determines prognosis in estrogen receptor-positive early breast cancer patients. Breast Cancer Res Treat 133:49-59 (2012). PubMed: 21796367
• Vrljicak P  et al. Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse. PLoS One 7:e40815 (2012). ChIP ; Mouse . PubMed: 22815831
• Román-Pérez E  et al. Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients. Breast Cancer Res 14:R51 (2012). IHC-P ; Human . PubMed: 22429463
• Riaz M  et al. High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes. Breast Cancer Res 14:R123 (2012). IHC-P ; Human . PubMed: 22967435
• Nagaishi M  et al. Slug, twist, and E-cadherin as immunohistochemical biomarkers in meningeal tumors. PLoS One 7:e46053 (2012). IHC-P ; Human . PubMed: 23029385
• El-Haibi CP  et al. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A 109:17460-5 (2012). ICC/IF ; Human . PubMed: 23033492
• Morel AP  et al. EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice. PLoS Genet 8:e1002723 (2012). WB . PubMed: 22654675
• Zabierowski SE  et al. Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor. Stem Cells 29:1752-62 (2011). WB . PubMed: 21948558
• Mamaeva D  et al. Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord. BMC Neurosci 12:99 (2011). IHC-P ; Human . PubMed: 21985235
• Kitase Y  et al. Spatiotemporal localization of periostin and its potential role in epithelial-mesenchymal transition during palatal fusion. Cells Tissues Organs 193:53-63 (2011). IHC-P ; Mouse . PubMed: 21051860
• Soini Y  et al. Transcription factors zeb1, twist and snai1 in breast carcinoma. BMC Cancer 11:73 (2011). IHC-P ; Human . PubMed: 21324165
• Katz E  et al. A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk. Br J Cancer 103:401-10 (2010). IHC-P ; Human . PubMed: 20628393
• Whipple RA  et al. Epithelial-to-mesenchymal transition promotes tubulin Detyrosination and Microtentacles that enhance endothelial engagement. Cancer Res 70:8127-37 (2010). WB, ICC/IF ; Human . PubMed: 20924103
• Degerman S  et al. Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures. Aging Cell 9:220-35 (2010). WB ; Human . PubMed: 20089118
• Valdés-Mora F  et al. TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer. Ann Surg Oncol 16:78-87 (2009). PubMed: 19002529
• Lee YB  et al. Twist-1 regulates the miR-199a/214 cluster during development. Nucleic Acids Res 37:123-8 (2009). WB ; Mouse . PubMed: 19029138
• Massoumi R  et al. Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J Exp Med 206:221-32 (2009). WB, ChIP ; Human . PubMed: 19124656
• von Burstin J  et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. Gastroenterology 137:361-71, 371.e1-5 (2009). WB ; Mouse . PubMed: 19362090
• Cheng GZ  et al. Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic Function. J Biol Chem 283:14665-73 (2008). WB ; Human . PubMed: 18353781