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ab50887 has been referenced in 82 publications.
Ito N et al.Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency.Sci Rep 8:1634 (2018).
PubMed: 29374279
Puglisi R et al.SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma.Oncotarget 9:7567-7581 (2018).
PubMed: 29484133
Qiao W et al.Prognostic and clinicopathological value of Twist expression in breast cancer: A meta-analysis.PLoS One 12:e0186191 (2017).
PubMed: 29016671
Yang RM et al.miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis.Cell Death Dis 8:e3129 (2017).
WB
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PubMed: 29048402
Ihira K et al.EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis.Oncotarget : (2017).
WB
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PubMed: 28088786
Bouard C et al.Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach.BMC Struct Biol 17:6 (2017).
PubMed: 28521820
Wang C et al.Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/ß-catenin signaling pathways in hepatocellular and colorectal carcinoma cells.Oncotarget 8:1092-1109 (2017).
WB
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Human
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PubMed: 27901475
Wang T et al.Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/ß-catenin signaling pathway.Oncotarget 8:18991-19012 (2017).
WB
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Human
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PubMed: 28177909
Xiong H et al.Twist1 Enhances Hypoxia Induced Radioresistance in Cervical Cancer Cells by Promoting Nuclear EGFR Localization.J Cancer 8:345-353 (2017).
WB, ICC/IF
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Human
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PubMed: 28261334
Luan X et al.HMGB1 is negatively correlated with the development of endometrial carcinoma and prevents cancer cell invasion and metastasis by inhibiting the process of epithelial-to-mesenchymal transition.Onco Targets Ther 10:1389-1402 (2017).
PubMed: 28424555
Wang S et al.Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/ß-catenin signaling pathway.Sci Rep 7:6215 (2017).
PubMed: 28740094
Khoshgoo N et al.MicroRNA-200b regulates distal airway development by maintaining epithelial integrity.Sci Rep 7:6382 (2017).
PubMed: 28743913
Zhang D et al.Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway.Int J Oncol 50:1513-1530 (2017).
WB
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Human
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PubMed: 28339091
Opinto G et al.Hierarchical clustering analysis identifies metastatic colorectal cancers patients with more aggressive phenotype.Oncotarget 8:87782-87794 (2017).
IHC-P
;
Human
.
PubMed: 29152120
Samaranayake GJ et al.Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer.Nat Commun 8:1204 (2017).
PubMed: 29089489
Yang J et al.HIF-2a promotes the formation of vasculogenic mimicry in pancreatic cancer by regulating the binding of Twist1 to the VE-cadherin promoter.Oncotarget 8:47801-47815 (2017).
PubMed: 28599281
Kim YH et al.Senescent tumor cells lead the collective invasion in thyroid cancer.Nat Commun 8:15208 (2017).
IHC
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PubMed: 28489070
Dongre A et al.Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas.Cancer Res 77:3982-3989 (2017).
WB
.
PubMed: 28428275
Lee YS et al.Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways.Oncotarget 7:36842-36853 (2016).
WB
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PubMed: 27167205
Wei C et al.Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein.Sci Rep 6:29822 (2016).
IHC-P
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Human
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PubMed: 27412325
Krstic M et al.The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer.BMC Cancer 16:671 (2016).
WB
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Human
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PubMed: 27553211
Ito M et al.Evaluation of aldehyde dehydrogenase 1 and transcription factors in both primary breast cancer and axillary lymph node metastases as a prognostic factor.Breast Cancer 23:437-44 (2016).
PubMed: 25599843
Cho MS et al.Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial-Mesenchymal Transition.J Immunol 196:1412-8 (2016).
PubMed: 26718342
Kim MS et al.Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer.Sci Rep 6:33899 (2016).
WB
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PubMed: 27654855
Bildsoe H et al.Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest.Data Brief 9:372-375 (2016).
ChIP
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PubMed: 27699189
Wu SY et al.A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.Nat Commun 7:11169 (2016).
ChIP
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Human
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PubMed: 27041221
Bouard C et al.Deciphering the molecular mechanisms underlying the binding of the TWIST1/E12 complex to regulatory E-box sequences.Nucleic Acids Res 44:5470-89 (2016).
WB
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Human
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PubMed: 27151200
Sun X et al.MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist.J Exp Clin Cancer Res 35:10 (2016).
WB
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Human
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PubMed: 26762267
Sun T et al.The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation.J Biol Chem 291:11518-28 (2016).
PubMed: 26975371
Chen D et al.MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1a-TWIST signaling axis in breast cancer.Oncotarget 6:32701-12 (2015).
PubMed: 26196741
Grzegrzolka J et al.Expression of EMT Markers SLUG and TWIST in Breast Cancer.Anticancer Res 35:3961-8 (2015).
Human
.
PubMed: 26124343
Wei SC et al.Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.Nat Cell Biol 17:678-88 (2015).
ICC/IF
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Human
.
PubMed: 25893917
Zheng S et al.Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators.J Immunol 195:217-26 (2015).
WB, ChIP
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Human
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PubMed: 26019273
Mego M et al.Relationship between circulating tumor cells and epithelial to mesenchymal transition in early breast cancer.BMC Cancer 15:533 (2015).
IHC-P
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Human
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PubMed: 26194471
Meier D et al.Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes.PLoS One 10:e0137229 (2015).
ChIP
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PubMed: 26361389
Piskareva O et al.The development of cisplatin resistance in neuroblastoma is accompanied by epithelial to mesenchymal transition in vitro.Cancer Lett N/A:N/A (2015).
PubMed: 25960282
Benzoubir N et al.Gamma-smooth muscle actin expression is associated with epithelial-mesenchymal transition and stem-like properties in hepatocellular carcinoma.PLoS One 10:e0130559 (2015).
Human
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PubMed: 26110787
Nordfors K et al.
Twist predicts poor outcome of patients with astrocytic glioma.
J Clin Pathol 68:905-12 (2015).
Human
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PubMed: 26163539
Zhao L et al.Bufalin inhibits TGF-ß-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-ß receptors.Int J Mol Med : (2015).
Human
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PubMed: 26133118
Li J et al.Endothelial TWIST1 promotes pathological ocular angiogenesis.Invest Ophthalmol Vis Sci 55:8267-77 (2014).
IHC
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Mouse
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PubMed: 25414194
Fukai J et al.Intracranial extension of adenoid cystic carcinoma: potential involvement of EphA2 expression and epithelial-mesenchymal transition in tumor metastasis: a case report.BMC Res Notes 7:131 (2014).
Human
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PubMed: 24606764
Xu Y et al.SRC-1 and Twist1 expression positively correlates with a poor prognosis in human breast cancer.Int J Biol Sci 10:396-403 (2014).
IHC
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Human
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PubMed: 24719557
Li A et al.Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.Gastroenterology 146:1386-96.e1-17 (2014).
WB, ICC/IF
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Mouse
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PubMed: 24462734
Loebel DA et al.Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterning.PLoS One 9:e98945 (2014).
ICC/IF
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Mouse
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PubMed: 24893291
Qiang L et al.Regulation of cell proliferation and migration by p62 through stabilization of Twist1.Proc Natl Acad Sci U S A 111:9241-6 (2014).
PubMed: 24927592
Zhang P et al.ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.Nat Cell Biol 16:864-75 (2014).
PubMed: 25086746
D'Angelo RC et al.TIMP-1 via TWIST1 induces EMT phenotypes in human breast epithelial cells.Mol Cancer Res 12:1324-33 (2014).
Human
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PubMed: 24895412
Lu H et al.A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.Nat Cell Biol 16:1105-17 (2014).
PubMed: 25266422
Bai F et al.BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development.Cancer Res 74:6161-72 (2014).
PubMed: 25239453
Goodwin JM et al.An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.Mol Cell 55:436-50 (2014).
PubMed: 25042806
Wushou A et al.Twist-1 up-regulation in carcinoma correlates to poor survival.Int J Mol Sci 15:21621-30 (2014).
PubMed: 25429425
Zhu DY et al.Twist1 correlates with poor differentiation and progression in gastric adenocarcinoma via elevation of FGFR2 expression.World J Gastroenterol 20:18306-15 (2014).
Human
.
PubMed: 25561797
Bernard JJ et al.Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells.J Carcinog Mutagen 5:2157-2518 (2014).
WB
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Mouse
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PubMed: 25821644
Bai Y et al.Bmp signaling represses Vegfa to promote outflow tract cushion development.Development 140:3395-402 (2013).
IHC-P
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Mouse
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PubMed: 23863481
Liang YJ et al.MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer.Carcinogenesis 34:713-22 (2013).
WB
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Human
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PubMed: 23250910
Chu IM et al.Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß.PLoS One 8:e61125 (2013).
WB
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PubMed: 23577196
Malaquin N et al.Senescent fibroblasts enhance early skin carcinogenic events via a paracrine MMP-PAR-1 axis.PLoS One 8:e63607 (2013).
WB
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Human
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PubMed: 23675494
Xu Y et al.Inducible knockout of twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting twist1 as a preferential cancer target.Am J Pathol 183:1281-92 (2013).
PubMed: 23906809
Toll A et al.Epithelial to mesenchymal transition markers are associated with an increased metastatic risk in primary cutaneous squamous cell carcinomas but are attenuated in lymph node metastases.J Dermatol Sci 72:93-102 (2013).
PubMed: 23928229
Stewart CA et al.CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development.Mol Endocrinol 27:1442-54 (2013).
PubMed: 23904126
Arumugam A et al.Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis.PLoS One 8:e80076 (2013).
Human
.
PubMed: 24260338
Dong P et al.Identification of KLF17 as a novel epithelial to mesenchymal transition inducer via direct activation of TWIST1 in endometrioid endometrial cancer.Carcinogenesis N/A:N/A (2013).
PubMed: 24220291
Das RK et al.Epithelio-mesenchymal transitional attributes in oral sub-mucous fibrosis.Exp Mol Pathol 95:259-69 (2013).
IHC-P
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Human
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PubMed: 23994666
van Nes JG et al.Co-expression of SNAIL and TWIST determines prognosis in estrogen receptor-positive early breast cancer patients.Breast Cancer Res Treat 133:49-59 (2012).
PubMed: 21796367
Vrljicak P et al.Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse.PLoS One 7:e40815 (2012).
ChIP
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Mouse
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PubMed: 22815831
Román-Pérez E et al.Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients.Breast Cancer Res 14:R51 (2012).
IHC-P
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Human
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PubMed: 22429463
Riaz M et al.High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes.Breast Cancer Res 14:R123 (2012).
IHC-P
;
Human
.
PubMed: 22967435
Nagaishi M et al.Slug, twist, and E-cadherin as immunohistochemical biomarkers in meningeal tumors.PLoS One 7:e46053 (2012).
IHC-P
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Human
.
PubMed: 23029385
El-Haibi CP et al.Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy.Proc Natl Acad Sci U S A 109:17460-5 (2012).
ICC/IF
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Human
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PubMed: 23033492
Morel AP et al.EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.PLoS Genet 8:e1002723 (2012).
WB
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PubMed: 22654675
Zabierowski SE et al.Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor.Stem Cells 29:1752-62 (2011).
WB
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PubMed: 21948558
Mamaeva D et al.Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord.BMC Neurosci 12:99 (2011).
IHC-P
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Human
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PubMed: 21985235
Kitase Y et al.Spatiotemporal localization of periostin and its potential role in epithelial-mesenchymal transition during palatal fusion.Cells Tissues Organs 193:53-63 (2011).
IHC-P
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Mouse
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PubMed: 21051860
Soini Y et al.Transcription factors zeb1, twist and snai1 in breast carcinoma.BMC Cancer 11:73 (2011).
IHC-P
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Human
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PubMed: 21324165
Katz E et al.A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk.Br J Cancer 103:401-10 (2010).
IHC-P
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Human
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PubMed: 20628393
Whipple RA et al.Epithelial-to-mesenchymal transition promotes tubulin Detyrosination and Microtentacles that enhance endothelial engagement.Cancer Res 70:8127-37 (2010).
WB, ICC/IF
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Human
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PubMed: 20924103
Degerman S et al.Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures.Aging Cell 9:220-35 (2010).
WB
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Human
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PubMed: 20089118
Valdés-Mora F et al.TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer.Ann Surg Oncol 16:78-87 (2009).
PubMed: 19002529
Lee YB et al.Twist-1 regulates the miR-199a/214 cluster during development.Nucleic Acids Res 37:123-8 (2009).
WB
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Mouse
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PubMed: 19029138
Massoumi R et al.Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma.J Exp Med 206:221-32 (2009).
WB, ChIP
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Human
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PubMed: 19124656
von Burstin J et al.E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex.Gastroenterology 137:361-71, 371.e1-5 (2009).
WB
;
Mouse
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PubMed: 19362090
Cheng GZ et al.Twist Is Transcriptionally Induced by Activation of STAT3 and Mediates STAT3 Oncogenic Function.J Biol Chem 283:14665-73 (2008).
WB
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Human
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PubMed: 18353781
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