Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 32 kDa.
IHC-P Use a concentration of 3 - 6 µg/ml.

Target

  • Function
    May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.
  • Tissue specificity
    Ubiquitous. Highly expressed in kidney, liver, placenta and lung.
  • Sequence similarities
    Contains 1 thioredoxin domain.
  • Cellular localization
    Membrane. Endoplasmic reticulum membrane. Predominantly found in the endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • PDIA11 antibody
    • Protein disulfide isomerase family A, member 11 antibody
    • Thioredoxin domain containing 1 antibody
    • Thioredoxin domain containing antibody
    • Thioredoxin domain-containing protein 1 antibody
    • Thioredoxin-related transmembrane protein 1 antibody
    • TMX antibody
    • TMX1 antibody
    • TMX1_HUMAN antibody
    • Transmembrane Trx-related protein antibody
    • TXNDC antibody
    • TXNDC1 antibody
    see all

Images

  • Anti-TXNDC antibody (ab37876) at 0.01 µg/ml + Human Liver lysate (35µg protein in RIPA buffer).
    Developed using the ECL technique

    Predicted band size : 32 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
  • ab37876 at 3.8 µg/ml staining TXNDC in Human spleen tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

References

ab37876 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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