Overview

  • Product name
    Anti-TXNDC2 antibody
  • Description
    Rabbit polyclonal to TXNDC2
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: corresponding to N terminal amino acids 5-114 of Human TXNDC2.

  • Positive control
    • Human testis tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P 1/750. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval.

Target

  • Function
    Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
  • Tissue specificity
    Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.
  • Sequence similarities
    Contains 1 thioredoxin domain.
  • Cellular localization
    Cytoplasm. In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
  • Information by UniProt
  • Database links
  • Alternative names
    • sperm-specific thioredoxin 1 antibody
    • Spermatid-specific thioredoxin-1 antibody
    • SPTRX antibody
    • Sptrx-1 antibody
    • SPTRX1 antibody
    • Thioredoxin domain containing 2 (spermatozoa) antibody
    • Thioredoxin domain-containing protein 2 antibody
    • TXND2_HUMAN antibody
    • Txndc2 antibody
    see all

Anti-TXNDC2 antibody images

  • ab121579, at a 1/750 dilution, staining TXNDC2 in paraffin-embedded Human testis by immunohistochemistry.

References for Anti-TXNDC2 antibody (ab121579)

ab121579 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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