Overview

  • Product nameAnti-TXNDC2 antibody
  • Description
    Rabbit polyclonal to TXNDC2
  • Tested applicationsSuitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: corresponding to N terminal amino acids 5-114 of Human TXNDC2.

  • Positive control
    • Human testis tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab121579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P 1/750. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol. Use buffer at pH 6 for antigen retrieval.

Target

  • FunctionProbably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
  • Tissue specificityTestis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.
  • Sequence similaritiesContains 1 thioredoxin domain.
  • Cellular localizationCytoplasm. In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
  • Information by UniProt
  • Database links
  • Alternative names
    • sperm-specific thioredoxin 1 antibody
    • Spermatid-specific thioredoxin-1 antibody
    • SPTRX antibody
    • Sptrx-1 antibody
    • SPTRX1 antibody
    • Thioredoxin domain containing 2 (spermatozoa) antibody
    • Thioredoxin domain-containing protein 2 antibody
    • TXND2_HUMAN antibody
    • Txndc2 antibody
    see all

Anti-TXNDC2 antibody images

  • ab121579, at a 1/750 dilution, staining TXNDC2 in paraffin-embedded Human testis by immunohistochemistry.

References for Anti-TXNDC2 antibody (ab121579)

ab121579 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"