Overview

  • Product nameAnti-TXNL2 antibody
    See all TXNL2 primary antibodies
  • Description
    Rabbit polyclonal to TXNL2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment containing a sequence corresponding to a region within amino acids 45 and 211 of Human TXNL2 (AAH05289).

  • Positive control
    • 293T, A431 and Raji cell lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab102472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.

Target

  • FunctionCritical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
  • Tissue specificityExpressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.
  • Sequence similaritiesContains 2 glutaredoxin domains.
    Contains 1 thioredoxin domain.
  • DomainThe thioredoxin domain lacks the two redox-active cysteines. This strongly suggests that it lacks thioredoxin activity.
  • Cellular localizationCytoplasm > cell cortex. Cytoplasm > myofibril > sarcomere > Z line. Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area. In the Z line, found associated with CSRP3.
  • Information by UniProt
  • Database links
  • Alternative names
    • glrx3 antibody
    • GLRX3_HUMAN antibody
    • GLRX4 antibody
    • Glutaredoxin 3 antibody
    • Glutaredoxin 4 antibody
    • Glutaredoxin-3 antibody
    • GRX3 antibody
    • GRX4 antibody
    • PICOT antibody
    • PKC interacting cousin of thioredoxin antibody
    • PKC theta interacting protein antibody
    • PKC-interacting cousin of thioredoxin antibody
    • PKC-theta-interacting protein antibody
    • PKCq interacting protein antibody
    • PKCq-interacting protein antibody
    • Thioredoxin like protein 2 antibody
    • Thioredoxin-like protein 2 antibody
    • TXNL3 antibody
    see all

Anti-TXNL2 antibody images

  • Anti-TXNL2 antibody (ab102472) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 37 kDa

References for Anti-TXNL2 antibody (ab102472)

ab102472 has not yet been referenced specifically in any publications.

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